107703-78-6 Usage
Description
ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL, also known as MDL 11,939, is a chemical compound with a complex molecular structure. It is characterized by its potent and selective properties as an SR-2 antagonist, which makes it a promising candidate for various applications in the pharmaceutical and medical industries.
Uses
Used in Pharmaceutical Industry:
ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL is used as a potent and selective SR-2 antagonist for the development of drugs targeting specific receptors in the body. Its high selectivity allows for more targeted and effective treatments with potentially fewer side effects.
Used in Psychological and Brain Disorders Treatment:
ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL is used as a therapeutic agent for the treatment of psychological and brain disorders. Its antagonistic properties can help modulate the activity of specific receptors, potentially leading to improved symptoms and overall well-being for patients suffering from these conditions.
Biological Activity
Potent, selective and orally active 5-HT 2 receptor antagonist (K i values are 0.54 and 81.6 nM at 5-HT 2A and 5-HT 2C receptors respectively).
Check Digit Verification of cas no
The CAS Registry Mumber 107703-78-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,7,0 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 107703-78:
(8*1)+(7*0)+(6*7)+(5*7)+(4*0)+(3*3)+(2*7)+(1*8)=116
116 % 10 = 6
So 107703-78-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H25NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19-20,22H,11-16H2
107703-78-6Relevant articles and documents
An efficient synthesis of N-alkyl-4-substituted 3H-pyridine-2,6-dione. Synthesis of isoguvacine and MDL-11,939
Chang, Meng-Yang,Chen, Shui-Tein,Chang, Nein-Chen
, p. 2321 - 2334 (2007/10/03)
An efficient route towards the synthesis of N-alkyl-4-substituted 3H-pyridine-2,6-dione using various N-alkyl-α-sulfonylacetamides and two α,β-unsaturated esters as starting materials is described. Isoguvacine and MDL-11,939 with have potential biological activities were synthesized via this strategy.
N-ARALKYL PIPERIDINE METHANOL DERIVATIVES AND THE USES THEREOF
-
, (2008/06/13)
This invention relates to a new class of compounds having important biochemical and pharmacological properties. More particularly, this invention relates to N-aralkyl piperidinemethanol derivatives which are potent and selective inhibitors of the binding