107752-85-2

Basic information

• Product Name: ethyl 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate
• Synonyms: ethyl 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate
• CAS NO: 107752-85-2
• Molecular Formula: C₁₈H₁₉NO₄
• Molecular Weight: 313.36
• Mol File: 107752-85-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 180 °C(Solv: ethanol (64-17-5))
• Boiling Point: 519.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• PKA: 3.53±0.40(Predicted)
• CAS DataBase Reference: ethyl 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate(107752-85-2)
• EPA Substance Registry System: ethyl 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate(107752-85-2)

Safety Data

• Hazardous Substances Data: 107752-85-2(Hazardous Substances Data)

Upstream product

• 2169-69-9 ethyl (E)-2-cyano-3-phenyl-2-propenoate 
• 504-02-9 1,3-cylohexanedione 
• 31771-33-2 2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine 
• 30182-67-3 1,3-Cyclohexanedione 
• 105-56-6 ethyl 2-cyanoacetate 
• 14533-87-0 (Z)-ethyl 2-cyano-3-phenylacrylate 
• 2025-40-3 ethyl benzylidenecyanoacetate 
• 100-52-7 benzaldehyde 

Downstream Products

• 1160476-35-6 C₁₈H₁₅NO₄ 

Relevant articles and documents

Solar Energy Mediated Green Synthesis of Tetrahydrobenzo[b]pyrans Using L-Ascorbic Acid as an Organocatalyst in Aqueous Medium

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Practical and efficient synthesis of tetrahydrobenzo[b]pyran using caffeine supported on silica as an ionic liquid solid acid catalyst

The new catalyst silica-caffeine hydrogen sulfate [SiO2-caff.]HSO4 was conveniently prepared from commercially available 3-chloropropyltriethoxysilane via immobilization on silica followed by reaction with caffeine. The catalyst prepared was then characterized by the FT-IR spectroscopy, TGA, EDX, and SEM techniques. It was found that this heterogeneous catalyst was a highly efficient one for the synthesis of tetrahydrobenzo[b]pyrans in good-to-high yields, and could be recovered by a simple filtration of the reaction solution and reused for five consecutive runs. The attractive features of this method are simple procedure, clean reaction, easy work-up, use of a reusable catalyst, and performing a multi-component reaction.

Synthesis of novel 2-aryloxy-3-(4-chlorophenyl)-8-substituted-5-aryl-8,9-dihydro-3H-chromeno[2,3-d]pyrimidine-4,6(5H,7H)-dione derivatives

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