107967-88-4

Basic information

• Product Name: (2-METHOXY-PHENOXY)-ACETIC ACID HYDRAZIDE
• Synonyms: 2-(2-methoxyphenoxy)ethanehydrazide;Acetohydrazide, 2-(2-methoxyphenoxy)-
• CAS NO: 107967-88-4
• Molecular Formula: C₉H₁₂N₂O₃
• Molecular Weight: 196.21
• Mol File: 107967-88-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 404.9°Cat760mmHg
• Flash Point: 198.7°C
• Appearance: /
• Density: 1.199g/cm³
• Vapor Pressure: 9.11E-07mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: (2-METHOXY-PHENOXY)-ACETIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHOXY-PHENOXY)-ACETIC ACID HYDRAZIDE(107967-88-4)
• EPA Substance Registry System: (2-METHOXY-PHENOXY)-ACETIC ACID HYDRAZIDE(107967-88-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 107967-88-4(Hazardous Substances Data)

Usage

General Description

(2-Methoxy-phenoxy)-acetic acid hydrazide is a chemical compound with the molecular formula C10H12N2O3. It is a hydrazide derivative of (2-methoxy-phenoxy)-acetic acid and is used in pharmaceutical research as an intermediate in the preparation of various organic compounds. The compound is also a potential herbicide and has been studied for its potential use in weed control. Additionally, (2-methoxy-phenoxy)-acetic acid hydrazide has been investigated for its potential use as a growth regulator in plants, as it has been shown to have effects on the growth and development of certain plant species.

InChI:InChI=1/C9H12N2O3/c1-13-7-4-2-3-5-8(7)14-6-9(12)11-10/h2-5H,6,10H2,1H3,(H,11,12)

Upstream product

• 13078-21-2 ethyl 2-(2-methoxyphenoxy)acetate 
• 1878-85-9 (2-methoxyphenoxy)acetic acid 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 21520-94-5 5-(2-methoxy-phenoxymethyl)-[1,3,4]oxadiazol-2-ylamine 
• 107951-93-9 C₁₇H₁₉N₃O₃S 
• 107951-92-8 C₁₆H₁₇N₃O₃S 
• 107967-89-5 C₁₆H₁₆ClN₃O₃S 
• 107967-90-8 C₁₇H₁₉N₃O₄S 
• 107951-94-0 C₁₆H₁₆ClN₃O₃S 
• 107951-95-1 C₁₈H₂₁N₃O₄S 
• 107951-96-2 C₂₀H₁₉N₃O₃S 
• 372164-13-1 2-(2-methoxyphenyl)oxymethyl-5-mercapto-1,2,4-triazole 
• 107952-04-5 5-(2-Methoxy-phenoxymethyl)-4-phenyl-4H-[1,2,4]triazole-3-thiol 
• 107952-05-6 5-(2-Methoxy-phenoxymethyl)-4-p-tolyl-4H-[1,2,4]triazole-3-thiol 
• 107952-06-7 4-(4-Chloro-phenyl)-5-(2-methoxy-phenoxymethyl)-4H-[1,2,4]triazole-3-thiol 
• 107952-07-8 4-(3-Chloro-phenyl)-5-(2-methoxy-phenoxymethyl)-4H-[1,2,4]triazole-3-thiol 
• 107952-08-9 4-(4-Ethoxy-phenyl)-5-(2-methoxy-phenoxymethyl)-4H-[1,2,4]triazole-3-thiol 

Relevant articles and documents

N-Amino-1,8-Naphthalimide is a Regenerated Protecting Group for Selective Synthesis of Mono-N-Substituted Hydrazines and Hydrazides

A new route to synthesis of various mono-N-substituted hydrazines and hydrazides by involving in a new C?N bond formation by using N-amino-1,8-naphthalimide as a regenerated precursor was invented. Aniline and phenylhydrazines are reproduced upon reacting these individually with 1,8-naphthalic anhydride followed by hydrazinolysis. The practicality and simplicity of this C?N dihalo alkanes; developed a synthon for bond formation protocol was exemplified to various hydrazines and hydrazides. N-amino-1,8-naphthalimide is suitable synthon for transformation for selective formation of mono-substituted hydrazine and hydrazide derivatives. Those are selective mono-amidation of hydrazine with acid halides; mono-N-substituted hydrazones from aldehydes; synthesis of N-aminoazacycloalkanes from acetohydrazide scaffold and inserted to hydroxy derivatives; distinct synthesis of N,N-dibenzylhydrazines and N-benzylhydrazines from benzyl halides; synthesis of N-amino-amino acids from α-halo esters. Ecofriendly reagent N-amino-1,8-naphthalimide was regenerated with good yields by the hydrazinolysis in all procedures.

Synthesis of Some New Substituted Mercaptotriazoles and Thiazolidones and Their Monoamine Oxidase Inhibitory and Anticonvulsant Properties

A number of 4-aryl-5-aryloxymethyl-3-mercapto-1,2,4(H)-triazoles (IV) and 2-arylimino-3-aryloxyacetamido-4-thiazolidones (V) have been synthesized.Some of these compounds inhibit rat brain monoamine oxidase (MAO) in vitro at a final concentration of 1E-3 mol/litre, but are found to be inactive against pentylenetetrazole induced seizures in mice at a dose of 80 mg/kg.