108309-78-0Relevant articles and documents
Synthesis and antibacterial activity of new 2-substituted penems. II
Nishi,Higashi,Soga,Takemura,Sato
, p. 357 - 369 (2007/10/02)
A series of new penems (4 ~ 17), having a bicyclic imidazole moiety as the C-2 substituent, has been synthesized. The antimicrobial activity of these compounds and their susceptibility to renal dehydropeptidase-1 (DHP-1) are elucidated, and their structure-activity relationships are discussed.