1084695-63-5

Basic information

• Product Name: C₁₇H₁₄O₆
• CAS NO: 1084695-63-5
• Molecular Weight: 314.295
• Mol File: 1084695-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₄O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₄O₆(1084695-63-5)
• EPA Substance Registry System: C₁₇H₁₄O₆(1084695-63-5)

Safety Data

• Hazardous Substances Data: 1084695-63-5(Hazardous Substances Data)

Upstream product

• 81474-46-6 4-bromo-7-methoxybenzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 40138-16-7 2-formylbenzene boronic acid 

Relevant articles and documents

Synthesis of unsymmetrical biphenyls as potent cytotoxic agents

Twenty-six unsymmetrical biphenyls were synthesized and evaluated for cytotoxic activity against DU145, A549, KB and KB-Vin tumor cell lines. Three compounds 27, 35 and 40 showed very potent activity against the HTCL panel with an IC50 value range of 0.04-3.23 μM. In addition, fourteen active compounds were all more potent against the drug-resistant KB-Vin cell line than the parental KB cell line. Preliminary SAR analysis indicated that two bulky substituents on the 2,2′-positions of unsymmetrical biphenyl skeleton are necessary and crucial for in vitro anticancer activity, thus providing a good starting point to develop unsymmetrical biphenyls as novel anticancer agents.