1086-43-7

Basic information

• Product Name: 2-(4-methoxyphenyl)-1-indanone
• Synonyms: 2-(4-methoxyphenyl)-1-indanone
• CAS NO: 1086-43-7
• Molecular Weight: 238.286
• Mol File: 1086-43-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-1-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-1-indanone(1086-43-7)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-1-indanone(1086-43-7)

Safety Data

• Hazardous Substances Data: 1086-43-7(Hazardous Substances Data)

Usage

General Description

2-(4-methoxyphenyl)-1-indanone is a chemical compound with the molecular formula C15H14O2. It is a ketone that consists of an indane core with a methoxyphenyl substituent at the 2-position. 2-(4-methoxyphenyl)-1-indanone is often used as a building block in the synthesis of various pharmaceuticals and organic compounds. It has been studied for its potential biological activities, including its anti-inflammatory and anti-cancer properties. Additionally, 2-(4-methoxyphenyl)-1-indanone has been investigated for its potential use in the development of new drug candidates for the treatment of various diseases. Overall, this compound has garnered interest in the scientific community for its diverse applications and potential therapeutic benefits.

Upstream product

• 637-69-4 4-Methoxystyrene 
• 1220094-19-8 (E)-1-formyl-2-[2-(4-methoxyphenyl)ethenyl]benzene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 83-33-0 inden-1-one 
• 100-44-7 benzyl chloride 
• 104-01-8 4-Methoxyphenylacetic acid 
• 100-52-7 benzaldehyde 
• 5840-58-4 2-(4-methoxyphenyl)-3-phenylpropanenitrile 
• 5840-59-5 3-phenyl-2-(4-methoxyphenyl)acrylonitrile 
• 39104-22-8 3-Phenyl-2-<4-methoxy-phenyl>-propionsaeure-chlorid 
• 1769-85-3 (±)-2-(4-methoxyphenyl)-3-phenylpropanoic acid 
• 104-47-2 p-methoxybenzylnitrile 

Downstream Products

• 102345-54-0 2-<4-Methoxy-phenyl>-3-<4-(2-diaethylamino-aethoxy)-phenyl>-inden 
• 145962-41-0 2-(4-methoxyphenyl)indanamine 
• 145962-42-1 2-(4-methoxyphenyl)-1-indanone oxime methyl ether 
• 107379-18-0 Bis<2-(4-methoxyphenyl)-3-indenyl> sulfide 
• 107379-17-9 2-(4-Methoxyphenyl)-3-indenethiol 

Relevant articles and documents

Rhodium-catalyzed intramolecular hydroacylation of 1,2-disubstituted alkenes for the synthesis of 2-substituted indanones

The intramolecular hydroacylation of 1,2-disubstituted alkenes was considered to be a challenging task due to the side reactions resulted from the lack of additional substituent at 1-position and the low activity caused by the steric hindrance of substituent at 2-position, and an asymmetric version has not been considered possible due to problems associated with the racemization of the products. We have partially solved these problems. Catalyzed by an activated diphosphine-Rh complex and reacted in a selected dihalogenated solvent, the intramolecular hydroacylation of o-(2-arylvinyl)benzaldehydes provided the corresponding 2-aryl-1-indanones in high yields, and its asymmetric variant using o-(2-alkylvinyl)benzaldehydes afforded chiral 2-alkyl-1-indanones in high yields and with moderate enantioselectivities.

AuI-catalyzed intramolecular cyclization of 2-alkenylphenyl carbonyl compounds: Exploring the oxophilic Lewis acidity of AuI species

A AuI-catalyzed intramolecular cyclization reaction of 2-alkenylphenyl carbonyl compounds to afford a variety of indene, indenol, and indanone ring systems was developed. In this process, AuI serves to activate the carbonyl group of β-keto esters, aldehydes, and ketones, preferentially exhibiting oxophilicity in the presence of C-C multiple bonds. Furthermore, β-keto esters could participate as the electrophilic partner in reactions with carbon nucleophile such as alkenes. Copyright