108640-66-0

Basic information

• Product Name: 2,5-Pyrrolidinedione, 1-[(4-methoxyphenyl)methyl]-
• CAS NO: 108640-66-0
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Mol File: 108640-66-0.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 1-[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 1-[(4-methoxyphenyl)methyl]-(108640-66-0)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 1-[(4-methoxyphenyl)methyl]-(108640-66-0)

Safety Data

• Hazardous Substances Data: 108640-66-0(Hazardous Substances Data)

Upstream product

• 254730-06-8 (S)-4-hydroxy-1-(4-methoxybenzyl)-2,5-pyrrolidinedione 
• 110-15-6 succinic acid 
• 2393-23-9 4-methoxy-benzylamine 
• 110-63-4 Butane-1,4-diol 
• 874-90-8 4-methoxybenzonitrile 
• 108-31-6 maleic anhydride 
• 58869-28-6 N-(4-methoxybenzyl)-4-hydroxybutanamide 
• 108-30-5 succinic acid anhydride 
• 123-56-8 Succinimide 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 1456904-99-6 ethyl 10-(4-methoxybenzyl)-9,11-dioxo-6,9,10,11-tetrahydro-5H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-8-carboxylate 
• 1005340-50-0 1-(4-methoxybenzyl)-5-methoxypyrrolidin-2-one 
• 110-63-4 Butane-1,4-diol 
• 2393-23-9 4-methoxy-benzylamine 
• 122123-86-8 5-hydroxy-1-(4-methoxybenzyl)pyrrolidin-2-one 
• 1175009-71-8 N-(p-methoxybenzyl)-3,7-dimethylene-cis-bicyclo[3.3.0]octane-1,5-dicarboximide 

Relevant articles and documents

PYRIDIN-2-ONE DERIVATIVES OF FORMULA (II) USEFUL AS EP3 RECEPTOR ANTAGONISTS

The present invention is directed to pyridin-2-one derivatives, pharmaceutical compositions containing them and their use as antagonists of the EP3 receptor, for the treatment of for example, impaired oral glucose tolerance, elevated fasting glucose, Type II Diabetes Mellitus, Syndrome X (also known as Metabolic Syndrome) and related disorders and complications thereof.

PYRIDIN-2-ONE DERIVATIVES OF FORMULA (III) USEFUL AS EP3 RECEPTOR ANTAGONISTS

The present invention is directed to pyridin-2-one derivatives, pharmaceutical compositions containing them and their use as antagonists of the EP3 receptor, for the treatment of for example, impaired oral glucose tolerance, elevated fasting glucose, Type II Diabetes Mellitus, Syndrome X (also known as Metabolic Syndrome) and related disorders and complications thereof.

Simple and efficient synthesis of N-alkyl and N-aryl succinimides in hot water

A new, simple synthesis of succinimides is described. The reactions were carried out under the ultimate green conditions excluding both catalyst and organic solvent by applying simple stirring at 100 °C. A wide variety of N-susbstituted succinimides have been prepared in high yields by using succinic acid and primary amines in hot water. Yield of N-alkyl substituted succinimides were found to be higher than those of N-aryl substituted succinimides.