108938-16-5

Basic information

• Product Name: 7-BROMO-5-METHYL-1H-INDOLE-2,3-DIONE
• Synonyms: BUTTPARK 50\07-85;CHEMBRDG-BB 4010945;7-BROMO-5-METHYL-1H-INDOLE-2,3-DIONE;7-BROMO-5-METHYLINDOLINE-2,3-DIONE;AKOS BBS-00001014;7-bromo-5-methyl-1H-indole-2,3-dione(SALTDATA: FREE);1H-Indole-2,3-dione, 7-broMo-5-Methyl-;7-broMo-5-Methyl-2,3-dihydro-1H-indole-2,3-dione
• CAS NO: 108938-16-5
• Molecular Formula: C₉H₆BrNO₂
• Molecular Weight: 240.05
• Product Categories: Indoline & Oxindole
• Mol File: 108938-16-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 176-180 °C
• Appearance: /
• Density: 1.714 g/cm³
• Refractive Index: 1.631
• PKA: 8.70±0.20(Predicted)
• CAS DataBase Reference: 7-BROMO-5-METHYL-1H-INDOLE-2,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMO-5-METHYL-1H-INDOLE-2,3-DIONE(108938-16-5)
• EPA Substance Registry System: 7-BROMO-5-METHYL-1H-INDOLE-2,3-DIONE(108938-16-5)

Safety Data

• Hazardous Substances Data: 108938-16-5(Hazardous Substances Data)

Usage

General Description

7-Bromo-5-methyl-1H-indole-2,3-dione is a chemical compound with the molecular formula C9H6BrNO2. It is a brominated derivative of 5-methylisatin, which is known for its diverse biological activities. 7-BROMO-5-METHYL-1H-INDOLE-2,3-DIONE has been studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceutical drugs. Its structure contains a bromine atom and a methyl group attached to the indole-2,3-dione core, which may contribute to its specific chemical and biological properties. Further research is needed to fully understand the potential uses and effects of 7-Bromo-5-methyl-1H-indole-2,3-dione.

InChI:InChI=1/C9H6BrNO2/c1-4-2-5-7(6(10)3-4)11-9(13)8(5)12/h2-3H,1H3,(H,11,12,13)

Upstream product

• 608-05-9 5-methyl-indole-2,3-dione 
• 124807-88-1 2-bromo-4-methyl-α-isonitrosoacetanilide 
• 583-68-6 2-bromo-p-toluidine 
• 1132-40-7 2-hydroxyimino-N-p-tolyl-acetamide 
• 106-49-0 p-toluidine 

Downstream Products

• 124807-89-2 7-bromo-1,5-dimethylindoline-2,3-dione 
• 13091-43-5 2-amino-3-bromo-5-methylbenzoic acid 
• 893651-25-7 C₁₉H₁₈BrN₃O₅ 
• 206551-32-8 methyl 2-amino-3-bromo-5-methyl benzoate 

Relevant articles and documents

Bicyclic heteroaryl compound with PAR4 antagonistic activity and application thereof

The invention discloses a bicyclic heteroaryl compound with PAR4 antagonistic activity and application thereof. The invention provides the bicyclic heteroaryl compound with PAR4 antagonistic activity,and the bicyclic heteroaryl compound has remarkable antagonistic activity on PAR4 in an in-vitro anti-platelet aggregation experiment, so that platelet aggregation is effectively inhibited, and the bicyclic heteroaryl compound can be used for preparing medicines for preventing or treating various thromboembolic diseases.

Synthesis of some Newer Biologically Active Substituted-3-((6-substituted-2-hydrazono)benzothiazolyl)-2-indolines. Part LIV

5-Bromo- and 5-methyl-7-bromoisatins (1a) have been synthesised and transformed into the corresponding 1-methyl analogs (1b). 1a and 1b have been condensed with 2-hydrazinobenzothiazoles to yield 3 and 4.Mannich condensation of 3 using morpholine and piperidine furnished the corresponding 1-morpholino/piperidinomethyl analogs (5).The compounds have been characterised by means of ir and pmr spectroscopy.