1090-16-0Relevant articles and documents
Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents
Benites, Julio,Valderrama, Jaime A.,Bettega, Karina,Pedrosa, Rozangela Curi,Calderon, Pedro Buc,Verrax, Julien
, p. 6052 - 6057 (2010)
Several members of the phenylamino-1,4-naphthoquinone series were prepared in order to investigate structure-activity relationships (SAR) and to explore the antitumor effects associated with this scaffold. The cytotoxic effects of the aminoquinones (ECsu
Synthesis and characterization of nitrogen and sulfur containing 1,4-naphthoquinones
Sayil, Cigdem,Kurban, Semih,Ibis, Cemil
, p. 1855 - 1867 (2013)
New N,S-disubstituted naphthoquinones were synthesized by reactions of S- and N-nucleophiles with 2,3-dichloro-1,4-naphthoquinone. 2-(Hexadecylthio)-3- (phenylamino)-naphthalene-1,4-dione 5a was synthesized by reaction of 2-chloro-3-(phenylamino)-naphthal
Synthesis, antimicrobial properties, and inhibition of catalase activity of 1,4-naphtho-and benzoquinone derivatives containing N-, S-, O-substituted
Kurban, Semih,Deniz, Nahide Gulsah,Sayil, Cigdem,Ozyurek, Mustafa,Guclu, Kubilay,Stasevych, Maryna,Zvarych, Viktor,Komarovska-Porokhnyavet, Olena,Novikov, Volodymyr
, (2019)
A series of new 1,4-naphtho-and benzoquinone derivatives possessing N-, S-, O-substituted groups which has not been reported yet has been synthesized from 2,3-dichloro-1,4-naphthoquinone 1 and 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione 15 involving
Spectroscopic and theoretical studies on the nucleophilic substitution of 2,3-dichloronaphthoquinone with para-substituted anilines in solid state via initial charge transfer complexation
Satheshkumar, Angupillai,Elango, Kuppanagounder P.
, p. 378 - 383,6 (2012)
Various spectroscopy techniques (UV-Vis, DRS, FT-IR, 1H NMR, LC-MS) and theoretical computations have been employed to investigate the mechanism of the nucleophilic substitution reaction of 2,3- dichloronaphthoquinone (DCNQ) with para-substitut
Thermolysis of 2-azido-3-(R-anilino)-1,4-naphthoquinones. Nitrene insertion versus hydrogen abstraction
Cárdenas-Chaparro, Agobardo,Leyva, Elisa,Loredo-Carrillo, Silvia E.,Martínez-Richa, Antonio,Platz, Matthew S.
supporting information, (2020/03/03)
2-chloro-3-(R-anilino)-1,4-naphthoquinones react with sodium azide upon refluxing in DMF. The thermochemistry of 2-azido-3-(R-anilino)-1,4-naphthoquinone is strongly modified by the substituent on aniline. Having an strong electron-donor like O-R results