1092351-90-0 Usage
General Description
2-Bromo-4-oxazolecarboxaldehyde is a chemical compound with the molecular formula C4H3BrNO2. It is an oxazole derivative with a bromine atom and an aldehyde functional group attached to the oxazole ring. 2-Bromo-4-oxazolecarboxaldehyde is used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a reagent in organic synthesis for the preparation of heterocyclic compounds. The presence of the bromine atom and the aldehyde group makes 2-Bromo-4-oxazolecarboxaldehyde a versatile and valuable intermediate in the production of complex organic molecules. However, it is important to handle this compound with caution, as it is considered harmful if swallowed, inhaled, or in contact with skin. Proper safety measures should be taken when handling and using 2-Bromo-4-oxazolecarboxaldehyde in laboratory and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 1092351-90-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,2,3,5 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1092351-90:
(9*1)+(8*0)+(7*9)+(6*2)+(5*3)+(4*5)+(3*1)+(2*9)+(1*0)=140
140 % 10 = 0
So 1092351-90-0 is a valid CAS Registry Number.
1092351-90-0Relevant articles and documents
Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks
Solomin, Vitalii V.,Radchenko, Dmytro S.,Slobodyanyuk, Evgeniy Y.,Geraschenko, Oleksandr V.,Vashchenko, Bohdan V.,Grygorenko, Oleksandr O.
, p. 2884 - 2898 (2019/03/07)
An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.
