1092797-19-7

Basic information

• Product Name: 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine 4-chloro-1-hydroxybutane-1-sulfonate
• Synonyms: 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine 4-chloro-1-hydroxybutane-1-sulfonate
• CAS NO: 1092797-19-7
• Molecular Weight: 443.973
• Mol File: 1092797-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine 4-chloro-1-hydroxybutane-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine 4-chloro-1-hydroxybutane-1-sulfonate(1092797-19-7)
• EPA Substance Registry System: 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine 4-chloro-1-hydroxybutane-1-sulfonate(1092797-19-7)

Safety Data

• Hazardous Substances Data: 1092797-19-7(Hazardous Substances Data)

Upstream product

• 54322-20-2 4-chloro-1-hydroxy-1-butanesulfonate sodium 

Relevant articles and documents

METHOD FOR THE PREPARATION OF HIGH PURITY ALMOTRIPTAN

A method for the preparation and purification of the substance of formula (I), i.e. 3-[2- (dimethylamino)ethyl]-5-(1-pyrrolidinylsulfonylmethyl)-1H-indole, which comprises (a) conversion of 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine of formula (III) by reaction with an organic or inorganic acid to a salt that is insoluble or poorly soluble in water, which is converted to 3-(2-aminoethyl)-5-(1-pyrrolidinylsulfonylmethyl)indole of formula (VII), which is further converted without isolation to a solution of the almotriptan base, which provides a crystalline salt of almotriptan with an organic or inorganic acid; (b) conversion of the salt of almotriptan to the almotriptan base, which separates from the solution in the crystalline form; (c) purification of the almotriptan base by crystallization from an organic solvent.