109389-24-4 Usage
Description
1-(BETA-D-2-DEOXYRIBOFURANOSYL)-4-(1,2,4-TRIAZOL-1-YL)-5-METHYLPYRIMIDIN-2-ONE is a complex organic compound with a unique molecular structure. It is characterized by its deoxyribofuranosyl and triazol-yl moieties, which contribute to its potential biological activities and applications in various fields.
Uses
1. Used in Antiviral Applications:
In the field of antiviral research, 1-(BETA-D-2-DEOXYRIBOFURANOSYL)-4-(1,2,4-TRIAZOL-1-YL)-5-METHYLPYRIMIDIN-2-ONE has demonstrated significant anti-HIV activities. It is used as an active pharmaceutical ingredient to combat the human immunodeficiency virus (HIV), potentially offering a new avenue for the development of antiretroviral therapies.
2. Used in Synthesis of Adducts:
1-(BETA-D-2-DEOXYRIBOFURANOSYL)-4-(1,2,4-TRIAZOL-1-YL)-5-METHYLPYRIMIDIN-2-ONE is also utilized as a reagent in the synthesis of adducts of deoxyadenosine (M1A) and deoxycytidine (M1C). These adducts are important in the study of DNA damage and repair mechanisms, as well as in the development of novel antiviral and anticancer agents.
3. Used in Pharmaceutical Research:
Due to its unique chemical structure and biological activities, 1-(BETA-D-2-DEOXYRIBOFURANOSYL)-4-(1,2,4-TRIAZOL-1-YL)-5-METHYLPYRIMIDIN-2-ONE holds promise for further research and development in the pharmaceutical industry. It may be explored for its potential applications in the treatment of various diseases, including viral infections and cancer.
4. Used in Chemical Synthesis:
In the field of chemical synthesis, 1-(BETA-D-2-DEOXYRIBOFURANOSYL)-4-(1,2,4-TRIAZOL-1-YL)-5-METHYLPYRIMIDIN-2-ONE can be employed as a key intermediate or building block for the development of new compounds with diverse applications, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 109389-24-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,3,8 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 109389-24:
(8*1)+(7*0)+(6*9)+(5*3)+(4*8)+(3*9)+(2*2)+(1*4)=144
144 % 10 = 4
So 109389-24-4 is a valid CAS Registry Number.
109389-24-4Relevant articles and documents
Direct synthesis, substitution, and structure of 1-(2'-deoxy-β-D-erythro-pentofuranosyl)-4-pentafluorophenylpyrimidin- 2H-one
Wallis,Spiers,Schwalbe,Fraser
, p. 3759 - 3762 (1995)
Direct methods have been developed to access the title nucleoside 1 from 2'-deoxyuridine (dU). The C-4 pentafluorophenyl group of 1 is readily displaced by amine nucleophiles forming N-4 substituted cytosines in good to excellent yields.
