109394-52-7

Basic information

• Product Name: 3-(4-chlorophenyl)-2,2-dimethyl-1-phenylpropan-1-one
• Synonyms: 3-(4-chlorophenyl)-2,2-dimethyl-1-phenylpropan-1-one
• CAS NO: 109394-52-7
• Molecular Weight: 272.774
• Mol File: 109394-52-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-chlorophenyl)-2,2-dimethyl-1-phenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-2,2-dimethyl-1-phenylpropan-1-one(109394-52-7)
• EPA Substance Registry System: 3-(4-chlorophenyl)-2,2-dimethyl-1-phenylpropan-1-one(109394-52-7)

Safety Data

• Hazardous Substances Data: 109394-52-7(Hazardous Substances Data)

Upstream product

• 4251-65-4 (4-chlorophenyl)acetaldehyde 
• 611-70-1 phenyl isopropyl ketone 
• 10409-54-8 2-bromo-2-methyl-1-phenyl-propan-1-one 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 108245-06-3 3-(4-chloro-phenyl)-2,2-dimethyl-propionic acid amide 

Relevant articles and documents

Building Congested Ketone: Substituted Hantzsch Ester and Nitrile as Alkylation Reagents in Photoredox Catalysis

For the first time, 4-alkyl Hantzsch esters were used to construct molecules with all-carbon quaternary centers by visible light-induced photoredox catalysis via transfer alkylation. Up to a 1500 h-1 turnover frequency was achieved in this reaction. Reactions of 4-alkyl Hantzsch nitriles as tertiary radical donors joined two contiguous all-carbon quaternary centers intermolecularly, and this chemistry was used to synthesize a common precursor of a class of hydroxysteroid dehydrogenase inhibitors.