109925-10-2

Basic information

• Product Name: 1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde
• Synonyms: 1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde;1，3-dimethyl-5-plenoxy-1 H-pyrazole-4-carboxaldehyde;1,3-dimethyl-5-phenoxypyrazole-4-carbaldehyde
• CAS NO: 109925-10-2
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.24
• Mol File: 109925-10-2.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde(109925-10-2)
• EPA Substance Registry System: 1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde(109925-10-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 109925-10-2(Hazardous Substances Data)

Usage

General Description

1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde is a chemical compound with a molecular formula C13H12N2O2. It is a yellow solid with a molecular weight of 224.25 g/mol. 1,3-Dimethyl-5-phenoxy-1H-pyrazole-4-carboxaldehyde is a pyrazole derivative and is often used in organic synthesis and medicinal chemistry. It is also known for its potential biological activities, including anti-inflammatory and antitumor properties. This chemical has been studied for its potential applications in pharmaceuticals and agrochemicals. Additionally, it is used as a building block in the synthesis of various biologically active compounds.

Upstream product

• 27006-76-4 5-chloro-4-formyl-1,3-dimethylpyrazole 
• 108-95-2 phenol 
• 2749-59-9 1,3-dimethyl-5-pyrazolone 
• 5203-77-0 1,3-dimethyl-1H-pyrazol-5-ol 

Downstream Products

• 149054-67-1 1,3-dimethyl-5-phenoxypyrazole-4-carbaldehyde oxime 
• 111812-58-9 fenpyroximate 
• 126763-67-5 1,3-dimethyl-5-phenoxypyrazol-4-carboaldoxime O-2,6,6-trimethylhept-2-ene-4-ynyl ether 
• 1424330-09-5 C₂₂H₂₄N₄O₂ 
• 149054-60-4 (CH₃)C₃N₂(OC₆H₅)(CH₃)COOH 
• 1620883-58-0 C₂₃H₂₁ClN₄O₃S 
• 110035-28-4 1,3-dimethyl-5-phenoxy-1H-pyrazole-4-carbaldehyde oxime 

Relevant articles and documents

Design of a simple and efficient synthesis for bioactive novel pyrazolyl-isoxazoline hybrids

A simple and new methodology has been developed for the synthesis of novel bioactive pyrazolyl-isoxazoline hybrids from a pyrazolyl-substituted oxime and various substituted allyloxybenzenes, which are easily available, inexpensive starting materials. All the novel synthesized target hybrids were characterized by NMR, IR, and mass spectroscopic techniques. We have employed some of the hybrid materials in anti-bacterial and anti-fungal activity studies. The hybrid materials 6m and 6p exhibited the best anti-bacterial and anti-fungal activities.

Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 5-trifluoromethylpyridyl moiety

In this study, in order to find novel biologically active pyrazole oxime compounds, a series of pyrazole oxime derivatives containing a 5-trifluoromethylpyridyl moiety were synthesized. Preliminary bioassays indicated that most title compounds were found to display good to excellent acaricidal activity against Tetranychus cinnabarinus at a concentration of 200 μg/mL, and some designed compounds still showed excellent acaricidal activity against Tetranychus cinnabarinus at the concentration of 10 μg/mL, especially since the inhibition rates of compounds 8e, 8f, 8l, 8m, 8n, 8p, and 8q were all 100.00%. Interestingly, some target compounds exhibited moderate to good insecticidal activities against Plutella xylostella and Aphis craccivora at a concentration of 200 μg/mL; furthermore, compounds 8e and 8l possessed outstanding insecticidal activities against Plutella xylostella under the concentration of 50 μg/mL.

Synthesis and biological activities of novel 1,3,4-thiadiazole-containing pyrazole oxime derivatives

A new library of 1,3,4-thiadiazole-containing pyrazole oximes was designed and synthesized. Their acaricidal and insecticidal activities were evaluated. Bioassay results indicated that some target compounds exhibited good acaricidal and insecticidal properties. Especially, compound 8m had 80% acaricidal activity against Tetranychus cinnabarinus at the concentration of 50?μg/mL, compound 8f displayed 100% insecticidal activities against Aphis craccivora at the concentration of 50?μg/mL, compounds 8r and 8w showed 100% insecticidal activities against Plutella xylostella at the concentration of 50?μg/mL. Furthermore, compounds 8r (LC50?=?19.61?μg/mL) and 8w (LC50?=?9.78?μg/mL) possessed comparable or even better insecticidal activities than the control Pyridalyl (LC50?=?17.40?μg/mL) against P. xylostella.