110033-82-4

Basic information

• Product Name: 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARIC*ACID-RESORUFI
• Synonyms: 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARIC*ACID-RESORUFI;1,2-di-O-lauryl-rac-glycero-3-glutaric*acid-resor;(6-Methylresorufin)ester;1,2-O-Dilauryl-rac-glycero-3-glutaricacid;resorufinyl 1,2-O-dilaurylglycero-3-glutarate;1,2-di-O-lauryl-rac-glycero-3-glutaric acid, resorufin;1,2-Di-O-decanoyl-rac-glycero-3-glutaric acid-resorufin labeled;1,2-Di-O-lauryl-rac-glycero-3-glutaric acid-resorufin labeled
• CAS NO: 110033-82-4
• Molecular Formula: C32H62O6
• Molecular Weight: 542.83108
• Mol File: 110033-82-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 788.8 °C at 760 mmHg
• Flash Point: 158 °C
• Appearance: /
• Density: 1.08 g/cm³
• Vapor Pressure: 7.42E-25mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: −20°C
• PKA: 1.01±0.20(Predicted)
• CAS DataBase Reference: 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARIC*ACID-RESORUFI(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARIC*ACID-RESORUFI(110033-82-4)
• EPA Substance Registry System: 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARIC*ACID-RESORUFI(110033-82-4)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 110033-82-4(Hazardous Substances Data)

Usage

Description

1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARICACID-RESORUFI, also known as O-Resorufinyl (Di-lauryl)glyceryl Glutarate, is a synthetic compound that serves as a substrate for the measurement of pancreatic lipase activity. It is characterized by its unique chemical structure, which includes two lauryl groups attached to the glyceryl backbone and a glutaric acid moiety. The presence of the resorufin group allows for the detection and quantification of lipase activity through fluorescence measurements.

Uses

Used in Pharmaceutical and Biomedical Research:
1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARICACID-RESORUFI is used as a substrate for pancreatic lipases activity in pharmaceutical and biomedical research. It is particularly useful for studying the function and regulation of pancreatic lipases, which play a crucial role in the digestion and absorption of dietary fats. By monitoring the activity of these enzymes, researchers can gain insights into various aspects of lipid metabolism and develop potential therapeutic strategies for managing lipid-related disorders.
Used in Diagnostic Applications:
In the field of diagnostics, 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARICACID-RESORUFI serves as a valuable tool for assessing pancreatic function. 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARICACID-RESORUFI can be used to evaluate the efficiency of lipase secretion and activity in patients, which may be indicative of pancreatic disorders or other health issues. By incorporating this substrate into diagnostic assays, clinicians can obtain a more accurate assessment of a patient's pancreatic health and tailor treatment plans accordingly.
Used in Drug Development:
1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARICACID-RESORUFI is also utilized in drug development for the screening and evaluation of potential pancreatic lipase inhibitors. These inhibitors can be useful in the treatment of obesity, type 2 diabetes, and other metabolic disorders by reducing the absorption of dietary fats. By using this substrate in high-throughput screening assays, researchers can identify novel compounds with lipase inhibitory activity and further optimize their therapeutic potential.

InChI:InChI=1/C44H67NO8/c1-3-5-7-9-11-13-15-17-19-21-30-49-34-38(50-31-22-20-18-16-14-12-10-8-6-4-2)35-51-43(47)24-23-25-44(48)52-37-27-29-40-42(33-37)53-41-32-36(46)26-28-39(41)45-40/h26-29,32-33,38H,3-25,30-31,34-35H2,1-2H3