110160-87-7Relevant articles and documents
ANTIMICROBIAL COMPOUNDS
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Paragraph 00105-00108, (2021/08/20)
Provided herein are compounds of formula (I) which comprise a cephalosporin antibiotic (present moiety X), bonded to a piperidine diazeniumdiolate (NONOate) or a salt thereof. Also provided are compositions that include a compound described herein and methods for promoting the dispersal of microorganisms from biofilms, inhibiting biofilm formation or development, treating and preventing biofilm-associated diseases and disorders or a Pseudomonas aeruginosa infection in a subject suffering from cystic fibrosis, and killing a biofilm-forming microorganism. (I)
Novel cephalosporin derivatives possessing a bicyclic heterocycle at the 3-position. Part II: Synthesis and antibacterial activity of 3-(5-methylthiazolo[4,5-c]pyridinium-2-yl)thiomethylcephalosporin derivatives and related compounds
Tsushima, Masaki,Kano, Yuko,Umemura, Eijiro,Iwamatsu, Katsuyoshi,Tamura, Atsushi,Shibahara, Seiji
, p. 1641 - 1653 (2007/10/03)
A series of cephalosporin derivatives with a thiazolopyridinium group at the 3-position was synthesized and evaluated for antibacterial activity. Some of these cephalosporin derivatives having a (5-alkylthiazolo[4,5-c]pyridinium-2-yl)thiomethyl group at t