110483-07-3

Basic information

• Product Name: Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)-
• Synonyms: Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)-;sphingolipid E;N-(3-hexadecyloxy-2-hydroxyprop-1-yl)-N-(2-hydroxyethyl)palmitamide
• CAS NO: 110483-07-3
• Molecular Formula: C37H75NO4
• Molecular Weight: 598
• EINECS: 408-110-4
• Mol File: 110483-07-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 689.1°Cat760mmHg
• Flash Point: 370.6°C
• Appearance: /
• Density: 0.926g/cm³
• Vapor Pressure: 5.63E-22mmHg at 25°C
• Refractive Index: 1.475
• PKA: 13.68±0.20(Predicted)
• CAS DataBase Reference: Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)-(110483-07-3)
• EPA Substance Registry System: Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)-(110483-07-3)

Safety Data

• Statements: 53
• Safety Statements: 61
• Hazardous Substances Data: 110483-07-3(Hazardous Substances Data)

Usage

General Description

Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)- is a complex chemical compound with a long, hydrophobic carbon chain and multiple hydroxy groups. It is commonly used as an emollient and moisturizing agent in various skincare and personal care products, including lotions, creams, and hair conditioners. Hexadecanamide, N-3-(hexadecyloxy)-2-hydroxypropyl-N-(2-hydroxyethyl)- has both hydrophilic and hydrophobic properties, making it effective in hydrating and softening the skin and hair. It also has the potential to act as a skin conditioning agent and may help improve the overall texture and appearance of the skin.

InChI:InChI=1/C37H75NO4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33-42-35-36(40)34-38(31-32-39)37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h36,39-40H,3-35H2,1-2H3

Upstream product

• 112-39-0 hexadecanoic acid methyl ester 
• 117606-92-5 cetyl glycidyl ether 
• 141-43-5 ethanolamine 
• 67780-92-1 N-(3-hexadecyloxy-2-hydroxypropyl)-N-2-hydroxyethylamine 
• 36653-82-4 1-Hexadecanol 

Downstream Products

• 119094-18-7 N-(3-hexadecyloxy-2-hydroxypropyl)-N-2-triphenylmethoxyethylhexadecanamide 

Relevant articles and documents

Synthesis method of amide derivative

The invention relates to the field of organic synthesis, and discloses a synthesis method of an amide derivative. The synthesis method comprises the following steps: generating glycidyl ether from alkyl alcohol and epoxy chloropropane under the actions of alkali and a catalyst, and carrying out aminolysis on the glycidyl ether and ethanolamine to obtain a secondary amine derivative; and carrying out aminolysis on the secondary amine derivative and alkyl carboxylic acid methyl ester to obtain the amide derivative. The synthesis method disclosed by the invention is simple, short in synthesis route, short in product production period and high in economic benefit, the total yield of the product is 45 to 55%, and the purity is up to 98%.

Composition for treating keratinous materials comprising a cationic associative polyurethane polymer and a protecting or conditioning agent

The invention concerns a composition for treating keratinous fibres, in particular human keratinous fibres such as hair, comprising in a physiologically acceptable medium, at least a protecting or conditioning agent, and further at least a cationic associative polyurethane polymer. The invention also concerns methods and devices using said composition.

External skin care preparation

An external skin care preparation comprising a compound represented by the following general formula (I) or (II), or a salt thereof: STR1 wherein R1 means an aliphatic hydrocarbon group having 9-25 carbon atoms, A and B denote specific groups respectively, R6 and R7 are individually an aliphatic hydrocarbon group having 10-26 carbon atoms, and R8 denotes a group --CH2 CH2 OH, --CH2 COOH or --COCH3.