1107641-09-7

Basic information

• Product Name: methyl 5'-oxo-2',3',4',5'-tetrahydro[1,1'-biphenyl]-4-carboxylate
• Synonyms: methyl 5'-oxo-2',3',4',5'-tetrahydro[1,1'-biphenyl]-4-carboxylate
• CAS NO: 1107641-09-7
• Molecular Weight: 230.263
• Mol File: 1107641-09-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: methyl 5'-oxo-2',3',4',5'-tetrahydro[1,1'-biphenyl]-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5'-oxo-2',3',4',5'-tetrahydro[1,1'-biphenyl]-4-carboxylate(1107641-09-7)
• EPA Substance Registry System: methyl 5'-oxo-2',3',4',5'-tetrahydro[1,1'-biphenyl]-4-carboxylate(1107641-09-7)

Safety Data

• Hazardous Substances Data: 1107641-09-7(Hazardous Substances Data)

Upstream product

• 930-68-7 cyclohexenone 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 504-02-9 1,3-cylohexanedione 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 364358-98-5 C₈H₇BrMgO₂ 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 

Downstream Products

• 579511-01-6 methyl 3'-hydroxy-[1,1'-biphenyl]-4-carboxylate 

Relevant articles and documents

ANTICONVULSANT COMPOUNDS

The present application relates to compounds and methods for reducing the severity of convulsant activity or epileptic seizures, or for the treatment of chronic or acute pain.

Copper/Selectfluor-System-Catalyzed Dehydration-Oxidation of Tertiary Cycloalcohols: Access to β-Substituted Cyclohex-2-enones, 4-Arylcoumarins, and Biaryls

A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols. Thus, by using 2 equiv. of Selectfluor at 25 C, the dehydration-oxidation of tertiary cyclohexanols and oxabenzocyclohexanols gave β-substituted cyclohex-2-enones and 4-arylcoumarins, respectively; whereas the dehydration-oxidation of tertiary cyclohexanols gave biaryls as the final products by using 2.5 equiv. of Selectfluor at 80 C. A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols.

Selective Heck reaction of aryl bromides with cyclopent-2-en-1-one or cyclohex-2-en-1-one

The selective Heck reaction of cyclopent-2-en-1-one or cyclohex-2-en-1-one with aryl bromides gives a simple access to the corresponding 3-arylcycloalk-2-en-1-ones. The choice of the base was found to be crucial to avoid the formation of 3-arylcyclopentan