11103-72-3 Usage
Description
Ruthenium red is a red-brown powder that is known for its inhibitory properties. It is a heavy metal coordination compound that can interact with various biological systems.
Uses
Used in Pharmaceutical Industry:
Ruthenium red is used as an inhibitor of mitochondrial ETC complexes I and III for studying the effects of these complexes on cellular respiration and energy production. This helps researchers understand the role of these complexes in various diseases and develop potential treatments.
Used in Biomedical Research:
Ruthenium red is used as an inhibitor of the ryanodine receptor (RyR) channels, which play a crucial role in calcium signaling and muscle contraction. By inhibiting these channels, researchers can study the mechanisms of calcium release and its impact on cellular functions.
Used in Dyes and Metabolites:
Ruthenium red, due to its distinct red-brown color, can be used as a dye in various applications. Additionally, its interaction with different metabolites can be studied for potential applications in detecting or tracking specific biochemical processes.
Biological Activity
Blocks Ca 2+ uptake and release from mitochondria, and Ca 2+ release from ryanodine-sensitive intracellular stores. Also blocks cell membrane-located capsaicin-activated cation channels (IC 50 = 14 nM) and voltage-sensitive Ca 2+ channels to inhibit neurotransmitter release.
Check Digit Verification of cas no
The CAS Registry Mumber 11103-72-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,1,0 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 11103-72:
(7*1)+(6*1)+(5*1)+(4*0)+(3*3)+(2*7)+(1*2)=43
43 % 10 = 3
So 11103-72-3 is a valid CAS Registry Number.
InChI:InChI=1/6ClH.14H3N.2H2O.3Ru/h6*1H;14*1H3;2*1H2;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6
