111055-87-9 Usage
Description
(E)-2-Fluoro-3-(4-fluorophenyl)-propenoic acid, ethyl ester is a chemical compound with the formula C11H9F2O2. It is an ethyl ester derivative of (E)-2-Fluoro-3-(4-fluorophenyl)-propenoic acid, which is a synthetic intermediate used in the production of pharmaceuticals and agrochemicals. This fluorinated derivative contains fluorine atoms, which can impart unique properties to the molecule, such as increased stability and bioavailability. It is often used in the research and development of new drugs and chemical products, and its properties make it an important building block in various chemical synthesis processes.
Uses
Used in Pharmaceutical Industry:
(E)-2-Fluoro-3-(4-fluorophenyl)-propenoic acid, ethyl ester is used as a synthetic intermediate for the development of new pharmaceuticals. Its fluorinated nature and unique properties contribute to the creation of more stable and bioavailable drug candidates.
Used in Agrochemical Industry:
In the agrochemical industry, (E)-2-Fluoro-3-(4-fluorophenyl)-propenoic acid, ethyl ester is used as a building block for the synthesis of various agrochemicals. Its properties can enhance the effectiveness and stability of these products, leading to improved performance in agricultural applications.
Used in Chemical Research and Development:
(E)-2-Fluoro-3-(4-fluorophenyl)-propenoic acid, ethyl ester is utilized in the research and development of new chemical products. Its unique properties make it a valuable compound for exploring novel chemical reactions and syntheses, potentially leading to the discovery of innovative materials and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 111055-87-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,0,5 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 111055-87:
(8*1)+(7*1)+(6*1)+(5*0)+(4*5)+(3*5)+(2*8)+(1*7)=79
79 % 10 = 9
So 111055-87-9 is a valid CAS Registry Number.
111055-87-9Relevant articles and documents
Stereoselective synthesis of fluoroalkenoates and fluorinated isoxazolidinones: N-substituents governing the dual reactivity of nitrones
Prakash, G.K. Surya,Zhang, Zhe,Wang, Fang,Rahm, Martin,Ni, Chuanfa,Iuliucci, Marc,Haiges, Ralf,Olah, George A.
supporting information, p. 831 - 838 (2014/01/23)
α-Fluoroalkenoates and 4-fluoro-5-isoxazolidinones are of vast interest due to their potential biological applications. We now demonstrate the syntheses of (E)-α-fluoroalkenoates and 4-fluoro-5-isoxazolidinones by the reactions between nitrones and α-fluoro-α-bromoacetate. By altering N-substituents in nitrones, (E)-α-fluoroalkenoates and 4-fluoro-5-isoxazolidinones can be achieved, respectively, with high chemo- and stereoselectivities. Experimental and computational studies have been conducted to elucidate the reaction mechanisms. Linear free energy relationship studies further revealed that the N-substituent effects are primarily of electronic origin. Copyright
Preparation et spectres de RMN, H, F et C-13 d'esters α-fluoro-cinnamiques para- et meta-substitues
Elkik, Elias,Francesch, Charlette
, p. 423 - 428 (2007/10/02)
In this publication we present H, F and C-13 NMR spectra of a series of para (11 examples) and meta (7 examples) substituted α-fluoro-Z-cinnamic esters and their corresponding acids.We also discuss the characteristics and scope of the various preparation