1110776-21-0

Basic information

• Product Name: tert-butyl 5-{[(1-benzothiophen-3-yl)sulfonyl](benzyl)amino}-3-[2-(diethylamino)ethoxy]-2-methyl-1H-indole-1-carboxylate
• Synonyms: tert-butyl 5-{[(1-benzothiophen-3-yl)sulfonyl](benzyl)amino}-3-[2-(diethylamino)ethoxy]-2-methyl-1H-indole-1-carboxylate
• CAS NO: 1110776-21-0
• Molecular Weight: 647.86
• Mol File: 1110776-21-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 5-{[(1-benzothiophen-3-yl)sulfonyl](benzyl)amino}-3-[2-(diethylamino)ethoxy]-2-methyl-1H-indole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5-{[(1-benzothiophen-3-yl)sulfonyl](benzyl)amino}-3-[2-(diethylamino)ethoxy]-2-methyl-1H-indole-1-carboxylate(1110776-21-0)
• EPA Substance Registry System: tert-butyl 5-{[(1-benzothiophen-3-yl)sulfonyl](benzyl)amino}-3-[2-(diethylamino)ethoxy]-2-methyl-1H-indole-1-carboxylate(1110776-21-0)

Safety Data

• Hazardous Substances Data: 1110776-21-0(Hazardous Substances Data)

Upstream product

• 18494-87-6 benzo[b]thiophene-3-sulfonyl chloride 
• 1110775-91-1 tert-butyl 5-benzylamino-3-[2-(diethylamino)ethoxy]-2-methyl-1H-indole-1-carboxylate 

Downstream Products

• 1110776-51-6 N-benzyl-N-{3-[2-(diethylamino)ethoxy]-2-methyl-1H-indol-5-yl}-1-benzothiophene-3-sulfonamide 

Relevant articles and documents

Palladium-catalyzed amination and sulfonylation of 5-bromo-3-[2- (diethylamino)ethoxy]indoles to potential 5-HT6 receptor ligands

A general and efficient palladium-catalyzed amination of 5-bromo-3-[2-(diethylamino)ethoxy]indoles has been developed. Best results are obtained in the presence of Pd(OAc)2 and 2-[di(1-adamantyl) phosphanyl]-1-phenylpyrrole as ligand. Subsequent sulfonylation gave novel indole derivatives, which are of interest as potentially biological active 5-HT6 receptor ligands. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.