111157-57-4

Basic information

• Product Name: 1,2,3,3aα,,4β,6,7,12,12aα,12bα-decahydro-2-methyl-4-phenylpyrrolo<3',4':1,2>indolizino<5,7-b>indole-1,3-dione
• CAS NO: 111157-57-4
• Molecular Weight: 371.439
• Mol File: 111157-57-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,3,3aα,,4β,6,7,12,12aα,12bα-decahydro-2-methyl-4-phenylpyrrolo<3',4':1,2>indolizino<5,7-b>indole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,3aα,,4β,6,7,12,12aα,12bα-decahydro-2-methyl-4-phenylpyrrolo<3',4':1,2>indolizino<5,7-b>indole-1,3-dione(111157-57-4)
• EPA Substance Registry System: 1,2,3,3aα,,4β,6,7,12,12aα,12bα-decahydro-2-methyl-4-phenylpyrrolo<3',4':1,2>indolizino<5,7-b>indole-1,3-dione(111157-57-4)

Safety Data

• Hazardous Substances Data: 111157-57-4(Hazardous Substances Data)

Upstream product

• 930-88-1 N-methylmaleimide 
• 100-52-7 benzaldehyde 
• 6052-68-2 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid 

Relevant articles and documents

X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES. PART 11. STEREOCHEMISTRY OF 1,3-DIPOLES GENERATED BY THE DECARBOXYLATIVE ROUTE TO AZOMETHINE YLIDES

The decarboxylative reaction of aryl aldehydes with cyclic secondary α-amino acids or primary α-amino acids in the presence of N-methyl- or N-phenyl-maleimide leads, via an intermediate azomethine ylide, to mixtures of bicyclic pyrrolidine cycloadducts in good yield.Cyclic secondary α-amino acids, where the carboxylic group is non-benzylic, give cycloadducts arising from a stereospecifically generated anti-dipole.Acyclic α-amino acids, and cyclic secondary α-amino acids with the carboxylic group located at a benzylic site, give rise to cycloadducts derived from both anti- and syn-configurations of the intermediate azomethine ylides.The reactions show little discrimination between endo- and exo-transition states for the cycloadditions.