1115-90-8

Basic information

• Product Name: 2-AMINOHEPTANOIC ACID
• Synonyms: 2-AMINOENANTHIC ACID;(+/-)-2-AMINOHEPTANEDIOIC ACID;2-AMINOHEPTANOIC ACID;(+/-)-2-AMINOPIMELIC ACID;D,L 2-AMINOHEPTANOIC ACID;ABA,ABSCISIC ACID;2-Aminoheptanoicacidpurum;NSC20146
• CAS NO: 1115-90-8
• Molecular Formula: C₇H₁₅NO₂
• Molecular Weight: 145.2
• Mol File: 1115-90-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: ~280 °C (dec.)
• Boiling Point: 250.954 °C at 760 mmHg
• Flash Point: 105.574 °C
• Appearance: /
• Density: 1.017 g/cm³
• Vapor Pressure: 0.00664mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.55±0.24(Predicted)
• BRN: 1722018
• CAS DataBase Reference: 2-AMINOHEPTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOHEPTANOIC ACID(1115-90-8)
• EPA Substance Registry System: 2-AMINOHEPTANOIC ACID(1115-90-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1115-90-8(Hazardous Substances Data)

Usage

Description

2-AMINOHEPTANOIC ACID, also known as alpha-amino heptanoic acid, is an alpha-amino acid derived from heptanoic acid with an amino group replacing one of the hydrogens at the 2nd position. This unique structure grants it potential applications in various fields due to its chemical properties.

Uses

Used in Pharmaceutical Industry:
2-AMINOHEPTANOIC ACID is used as a building block for the synthesis of various pharmaceutical compounds, such as antibiotics, due to its unique structure and reactivity. It can be incorporated into the development of new drugs with specific therapeutic properties.
Used in Biochemical Research:
In the field of biochemical research, 2-AMINOHEPTANOIC ACID serves as an important tool for studying protein structure and function. It can be used to create analogs of natural amino acids, which can help researchers understand the role of specific amino acids in protein folding, stability, and function.
Used in Nutritional Supplements:
2-AMINOHEPTANOIC ACID can be utilized as an ingredient in nutritional supplements, particularly those aimed at enhancing athletic performance or supporting muscle growth. Its unique structure may provide benefits that are not achievable with more common amino acids.
Used in Cosmetics Industry:
In the cosmetics industry, 2-AMINOHEPTANOIC ACID may be used as an active ingredient in skincare products, potentially offering anti-aging, moisturizing, or protective benefits due to its unique chemical properties.
Used in Chemical Synthesis:
2-AMINOHEPTANOIC ACID can be employed as an intermediate in the synthesis of various organic compounds, including specialty chemicals, dyes, and other industrial products. Its unique structure allows for the creation of novel compounds with specific applications.

InChI:InChI=1/C7H15NO2/c1-2-3-4-5-6(8)7(9)10/h6H,2-5,8H2,1H3,(H,9,10)

Upstream product

• 5440-46-0 acetylamino-pentyl-malonic acid diethyl ester 
• 616-88-6 2-n-pentyl malonic acid 
• 89776-66-9 amino-(5-methyl-[2]thienyl)-acetic acid 
• 110-53-2 1-Bromopentane 
• 2769-72-4 tert-Butyl isocyanoacetate 
• 7647-01-0 hydrogenchloride 
• 2624-01-3 2-bromoheptanoic acid 
• 7664-41-7 ammonia 
• 10035-10-6 hydrogen bromide 
• 71-41-0 pentan-1-ol 
• 4450-76-4 1-pentyl tosylate 
• 59427-08-6 Pentan-sulfonsaeure-p-tolylester 
• 6065-59-4 diethyl n-pentylmalonate 
• 111-71-7 heptanal 

Downstream Products

• 5703-20-8 2-benzoylamino-heptanoic acid 
• 1916-94-5 N-Acetoacetyl-N-benzyl-2-amino-heptansaeure 
• 1859-50-3 2-Benzylamino-heptansaeure 
• 127862-70-8 2-Benzyloxycarbonylamino-heptanoic acid 2,2,2-trifluoro-ethyl ester 
• 44902-01-4 (R)-2-aminoheptanoic acid 
• 44902-02-5 (2S)-2-aminoheptanoic acid 

Relevant articles and documents

Protein engineering by in vivo incorporation of non-natural amino acids: Control of incorporation of methionine analogues by methionyl-tRNA synthetase

The incorporation of non-natural amino acids is an important strategy for engineering novel chemical and physical properties into natural and artificial proteins. The incorporation of amino acids into proteins in vivo is controlled in large part by the aminoacyl-tRNA synthetases (AARS). We have measured kinetic constants for in vitro activation of a set of methionine analogues by methionyl-tRNA synthetase (MetRS) via the ATP-PP(i) exchange reaction. Activation of methionine analogues in vitro correlates well with the ability of these analogues to support protein synthesis in vivo, substantiating the critical role of the AARS in controlling the incorporation of non-natural amino acids into proteins. Methionine analogues with k(cat)/K(m) values 2000-fold lower than those for methionine can support synthesis of a typical target protein (mDHFR) under standard conditions of protein expression. The kinetic constants correlate well with observed protein yields from a conventional bacterial expression host, indicating that the MetRS activity of the host can control the level of protein synthesis under certain conditions. Furthermore, increasing the MetRS activity of the bacterial host results in increased protein synthesis in media supplemented with the methionine analogues homoallylglycine and norleucine. These results suggest new strategies for incorporation of non-natural amino acids via manipulation of the AARS activity of a bacterial host. (C) 2000 Elsevier Science Ltd.

Synthesis of L α amino acids structurally related to isoleucine

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Enantioselective organocatalytic synthesis of 2-oxopiperazines from aldehydes: Identification of the elusive epoxy lactone intermediate

An organocatalytic linchpin catalysis approach was envisaged to convert simple aldehydes into enantioenriched 2-oxopiperazines. A four-step reaction sequence (chlorination, oxidation, substitution, and cyclization) was developed and led to different substitution patterns in high yields and selectivities. The reaction mechanism was studied, and the previously elusive epoxy lactone intermediate was identified by HRMS.