1115951-84-2Relevant articles and documents
Metal-Free C=C Double Bond Cleavage on Enaminones for the Synthesis of α-Ketoamides by Free-Radical Aerobic Oxygenation
Yang, Yiming,Zhong, Guofeng,Fan, Junfen,Liu, Yunyun
supporting information, p. 4422 - 4425 (2019/06/24)
The tandem oxidation of the enaminone C=C double bond as well as subsequent C-N bond formation are realized under metal-free conditions by thermo-induced free radical transformation. In the presence of benzoyl peroxide (BPO) and N-iodosuccinimide (NIS), a
The syntheses of α-ketoamides vianBu4NI- catalyzed multiple sp3C-H bond oxidation of ethylarenes and sequential coupling with dialkylformamides
Du, Bingnan,Jin, Bo,Sun, Peipei
supporting information, p. 4586 - 4589 (2014/06/24)
The nBu4NI-catalyzed sequential C-O and C-N bond formation via multiple sp3C-H bond activation of ethylarenes, using N,N-dialkylformamide as the amino source, provided α-ketoamides with moderate yields. This journal is
Direct use of formamides as amino group sources via C-N bond cleavage: A catalytic oxidative synthesis of α-ketoamides from acetophenones and formamides under metal-free conditions
Zhao, Qiong,Miao, Tao,Zhang, Xiaobin,Zhou, Wei,Wang, Lei
, p. 1867 - 1873 (2013/04/10)
An efficient and direct use of formamides as amino group sources for the synthesis of α-ketoamides was developed under metal-free conditions. The reaction was based on the oxidative coupling of acetophenones with formamides and generated the desired products in good yields in the presence of t-BuOOH/I2/PhCO2H.