1116617-18-5Relevant articles and documents
Synthesis of methyl [6-(2-amino-1,3-thiazol-4-yl)-3-oxo-1,4-benzoxazin-2- yl]acetates as possible COX-2 / 5-LOX inhibitors
Jagath Reddy,Srinivasa Rao,Jayaveera,Sailaja,Reddanna,Bharat Reddy
, p. 95 - 100 (2008/09/20)
A series of methyl [6-(2-aminothiazol-4-yl)-3-oxo-1,4-benzoxazin-2-yl] acetates (3-5) have been synthesized and tested for COX-2 (Cyclooxygenase) / 5-LOX (Lipoxygenase) inhibitory activity. Some of the compounds exhibited notable 5-LOX inhibitory activity.