1120-74-7

Basic information

• Product Name: (RS)-2-chloro-4-hydroxy-butyraldehyde (RS)-cyclohemiacetal
• CAS NO: 1120-74-7
• Molecular Weight: 122.551
• Mol File: 1120-74-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (RS)-2-chloro-4-hydroxy-butyraldehyde (RS)-cyclohemiacetal(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-2-chloro-4-hydroxy-butyraldehyde (RS)-cyclohemiacetal(1120-74-7)
• EPA Substance Registry System: (RS)-2-chloro-4-hydroxy-butyraldehyde (RS)-cyclohemiacetal(1120-74-7)

Safety Data

• Hazardous Substances Data: 1120-74-7(Hazardous Substances Data)

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 

Downstream Products

• 1023-94-5 1,1-diphenylbutan-1,4-diol 

Relevant articles and documents

Oxidation of olefins by palladium(II): Part 17. An asymmetric chlorohydrin synthesis catalyzed by a bimetallic palladium(II) complex

Previous studies showed that oxidation of α-olefins with monometallic catalysts containing chiral diphosphines and diamines gave chlorohydrins with poor to good enantioselectivites (28-82% ee). The present studies demonstrate that bimetallic catalysts containing a β-triketone and bridging chiral diphosphine and diamines are excellent catalysts for this reaction giving enantioselectivites considerably higher than the monometallic catalysts. Enantioselectivities were more than 50% for most olefins tested. The highest optical purities were 94% ee for propene and 93% ee for allylphenyl ether. A useful feature of this asymmetric synthesis is the fact it is a net air oxidation.