1120327-20-9Relevant articles and documents
The synthesis of substituted piperazine-cholesterol conjugates for use as components of nucleic acid transfection lipoplexes
Ul Islam, Rafique,Johnson, Myron M.,Mohammed, Raushaan,Hean, Justin,Arbuthnot, Patrick,De Koning, Charles B.,Van Otterlo, Willem A.L.
experimental part, p. 88 - 94 (2011/06/09)
A small library of cholesterol-piperazine conjugates were synthesized by the reaction of cholesteryl chloroformate with a set of substituted piperazines in dichloromethane at room temperature. The conjugates, all obtained in good to excellent yields, were synthesized to be key components of nucleic acid transfection lipoplexes.