1122-25-4

Basic information

• Product Name: (2Z)-2-ethylidenecyclohexan-1-one
• CAS NO: 1122-25-4
• Molecular Formula: C₈H₁₂O
• Molecular Weight: 124.183
• Mol File: 1122-25-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 205.2°Cat760mmHg
• Flash Point: 75.2°C
• Density: 1.033g/cm³
• CAS DataBase Reference: (2Z)-2-ethylidenecyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-2-ethylidenecyclohexan-1-one(1122-25-4)
• EPA Substance Registry System: (2Z)-2-ethylidenecyclohexan-1-one(1122-25-4)

Safety Data

• Hazardous Substances Data: 1122-25-4(Hazardous Substances Data)

Usage

Description

(2Z)-2-ethylidenecyclohexan-1-one, also known as Ethylidenecyclohexanone, is a cyclic ketone with a molecular formula of C9H14O. It features a double bond at the 2 position and an ethylidene substituent, giving it a distinct chemical structure. (2Z)-2-ethylidenecyclohexan-1-one is recognized for its aromatic properties, characterized by a pleasant, sweet, and fruity aroma.

Uses

Used in Food Industry:
(2Z)-2-ethylidenecyclohexan-1-one is used as a flavoring agent for its ability to impart a pleasant, sweet, and fruity aroma to various food products.
Used in Fragrance and Perfume Industry:
(2Z)-2-ethylidenecyclohexan-1-one is utilized in the production of fragrances and perfumes due to its attractive and versatile scent profile, enhancing the olfactory experience of these products.
Used in Pharmaceutical Industry:
(2Z)-2-ethylidenecyclohexan-1-one has potential applications in the pharmaceutical industry, although the specific uses are not detailed in the provided materials. Its aromatic properties may contribute to the development of medications or pharmaceutical formulations.
Used in Cosmetic Industry:
Similarly, in the cosmetic industry, (2Z)-2-ethylidenecyclohexan-1-one may find use due to its aromatic qualities, potentially being incorporated into cosmetic products to provide a pleasant scent or enhance product appeal.

Upstream product

• 917-64-6 methyl magnesium iodide 
• 15839-23-3 2-(i-propoxymethylene)cyclohexanone 
• 60-29-7 diethyl ether 
• 108-94-1 cyclohexanone 
• 75-07-0 acetaldehyde 
• 100-64-1 cyclohexanone-oxime 
• 5396-14-5 ethyl 2-oxo-2-(2-oxocyclohexyl)acetate 
• 75-16-1 methylmagnesium bromide 
• 1193-63-1 Cyclohexanone-2-carbaldehyde 
• 497-26-7 2-methyl-1,3-dioxolane 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 766-20-1 2,4-dimethyl-[1,3]dioxane 
• 105-57-7 diethyl acetal 
• 670-80-4 4-cyclohexen-1-ylmorpholine 

Downstream Products

• 99175-42-5 (2-ethylidene-cyclohexyl)-dimethyl-amine 
• 4908-53-6 2-(3-Methyl-3-nitro-2-butyl)-cyclohexan-1-on 
• 64165-18-0 6-hydroxyoctanoic acid 
• 89225-08-1 2-[1-(5-Methyl-furan-2-yl)-ethyl]-cyclohexanone 
• 89225-09-2 2-[1-(5-Isopropyl-furan-2-yl)-ethyl]-cyclohexanone 
• 75359-66-9 2-(1,3-Dimethyl-but-3-enyl)-cyclohexanone 
• 75359-67-0 2-(1-Methyl-but-3-enyl)-cyclohexanone 
• 168482-51-7 2-(N,N-dimethylaminomethyl)-2-(1-trimethylstannylethyl)-1-cyclohexane 
• 168482-48-2 2-(1-trimethylstannylethyl)-1-cyclohexanone 
• 168482-52-8 1-(trimethylsilyloxy)-2-(1-trimethylstannylethyl)-1-cyclohexene 
• 35504-42-8 2-(1-acetoxyethyl)-1-ethynylcyclohexene 
• 33775-90-5 1-(2-Vinylidene-cyclohexyl)-ethanol 
• 88827-81-0 7-furfurylidene-4-methyl-3-phenyl-1-oxa-2-aza-spiro[4.5]dec-2-en-6-one 
• 92870-14-9 4-methyl-3-phenyl-1-oxa-2-aza-spiro[4.5]dec-2-en-6-one oxime 

Relevant articles and documents

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Base-promoted ring expansion of 3-aminopyrimidine-2-thiones into 1,2,4-triazepine-3-thiones

A base-promoted ring expansion of 3-amino-4-hydroxyhexahydropyrimidine-2-thiones into 2,4,5,6-tetrahydro-3H-1,2,4-triazepine-3-thiones has been developed. Experimental data and DFT calculations showed that the reaction proceeded through fast formation of intermediate acyclic isomers of pyrimidines followed by their slow cyclization into triazepines. The starting hydroxypyrimidines were prepared by reaction of α,β-unsaturated ketones or β-alkoxy ketones with HNCS followed by treatment of the obtained β-isothiocyanato ketones with hydrazine. Triazepine-3-thiones were transformed into their 3-oxo analogs by oxidation with H2O2 under basic conditions.

NEW DEVELOPMENTS OF THE WHARTON TRANSPOSITION

The synthetically useful Wharton transposition can be improved by using a more adequate procedure in the critical step of the intermediate α-epoxyhydrazone cleavage.Either for stable hydrazones or unstable ones, the yield of the transposed allylic alcohol is increased by treatment under anhydrous conditions with highly basic reagents (KDA in the former case, NEt3 in the latter).

Reaction of Enamines with Acetals or Trialkyl Orthoformates Activated by Lewis Acids

Enamines, prepared readily from various carbonyl compounds, react with acetals or trialkyl orthoformates in the presence of Lewis acids such as BF3.OEt2 to give corresponding β-alkoxy carbonyl compounds or α-dialkoxymethyl carbonyl compounds in good yields.The reaction of dienamines with acetals or trialkyl orthoformates also selectively gives corresponding β,χ-unsaturated α-(α-alkoxyalkyl) carbonyl compounds or β,χ-unsatureted α-dialkoxymethyl carbonyl compounds in good yields.