112251-93-1

Basic information

• Product Name: 3-chloro-4-methyl-2-nitro-phenol
• Synonyms: 3-chloro-4-methyl-2-nitro-phenol
• CAS NO: 112251-93-1
• Molecular Weight: 187.583
• Mol File: 112251-93-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloro-4-methyl-2-nitro-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-4-methyl-2-nitro-phenol(112251-93-1)
• EPA Substance Registry System: 3-chloro-4-methyl-2-nitro-phenol(112251-93-1)

Safety Data

• Hazardous Substances Data: 112251-93-1(Hazardous Substances Data)

Upstream product

• 615-62-3 3-chloro-4-methylphenol 
• 112251-96-4 3-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone 
• 56180-49-5 4-chloro-4-methylcyclohexa-2,5-dien-1-one 
• 54788-38-4 2-chloro-4-methoxy-1-methylbenzene 

Downstream Products

• 112251-95-3 3-chloro-1-methoxy-4-methyl-2-nitro-benzene 

Relevant articles and documents

ipso NITRATION. XXIX. NITRATION OF SUBSTITUTED 4-METHYLANISOLES AND PHENOLS

Nitration of 2-chloro-4-methylanisole (1a) in acetic anhydride gives (Z)-4-chloro-3-methoxy-6-methyl-6-nitrocyclohexa-2,4-dienyl acetate (2a), 2-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone (3a), and 2-chloro-4-methyl-6-nitroanisole (4a).Similarly 2-bromo-4-methylanisole (1b) gives (Z)-4-bromo-3-methoxy-6-methyl-6-nitrocyclohexa-2,4-dienyl acetate (2b), 2-bromo-4-methyl-4-nitrocyclohexa-2,5-dienone (3b), and 2-bromo-4-methyl-6-nitroanisole (4b), whereas 4-methyl-2-nitro-anisole (1c) gives (Z)-3-methoxy-6-methyl-4,6-dinitrocyclohexa-2,4-dienyl acetate (2c), (Z)-3-methoxy-6-methyl-2,6-dinitrocyclohexa-2,4-dienyl acetate (7), and 4-methyl-2,6-dinitroanisole (4c).Nitration of 3-chloro-4-methylanisole (9a) gives 3-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone (10a), 3-chloro-4-methyl-2-nitro anisole (11a), and 5-chloro-4-methyl-2-nitroanisole (12a), and 4-methyl-3-nitroanisole (9c) gives (Z)-3-methoxy-6-methyl-5,6-dinitrocyclohexa-2,4-dienyl acetate (13), 4-methyl-2,3-dinitroanisole (11c), and 4-methyl-2,5-dinitroanisole (12c).Nitration of 2-chloro-4-methylphenol (14) in chloroform gives 3a and 2-chloro-4-methyl-6-nitrophenol (5a), and 3-chloro-4-methylphenol (15) gives dienone 10a, 3-chloro-4-methyl-2-nitrophenol (16), and 5-chloro-4-methyl-2-nitrophenol (17).