112279-71-7

Basic information

• Product Name: 4-AMINO-2,3-DIFLUOROBENZONITRILE
• Synonyms: 4-AMINO-2,3-DIFLUOROBENZONITRILE;2,3-Difluoro-4-aMinobenzonitrile
• CAS NO: 112279-71-7
• Molecular Formula: C₇H₄F₂N₂
• Molecular Weight: 154.1168664
• Mol File: 112279-71-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 108-110 °C
• Boiling Point: 269℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.36
• Vapor Pressure: 0.0076mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: 2-8°C(protect from light)
• PKA: -0.69±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-2,3-DIFLUOROBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-2,3-DIFLUOROBENZONITRILE(112279-71-7)
• EPA Substance Registry System: 4-AMINO-2,3-DIFLUOROBENZONITRILE(112279-71-7)

Safety Data

• Hazardous Substances Data: 112279-71-7(Hazardous Substances Data)

Usage

General Description

4-AMINO-2,3-DIFLUOROBENZONITRILE is a chemical compound with the molecular formula C7H3F2N. It is a pale yellow crystalline solid with a molecular weight of 145.1 g/mol. 4-AMINO-2,3-DIFLUOROBENZONITRILE is used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in the production of dyes and other organic compounds. 4-AMINO-2,3-DIFLUOROBENZONITRILE is a potentially hazardous material and should be handled with caution, following proper safety protocols and guidelines for handling and storage.

InChI:InChI=1/C7H4F2N2/c8-6-4(3-10)1-2-5(11)7(6)9/h1-2H,11H2

Upstream product

• 112279-73-9 4'-cyano-2',3'-difluoroacetanilide 
• 18355-79-8 N-(2,3-difluoro-phenyl)-acetamide 
• 4519-40-8 2,3-difluoroanilline 
• 7732-18-5 water 

Downstream Products

• 112279-73-9 4'-cyano-2',3'-difluoroacetanilide 

Relevant articles and documents

Tandem optimization of target activity and elimination of mutagenic potential in a potent series of N-aryl bicyclic hydantoin-based selective androgen receptor modulators

Pharmacokinetic studies in cynomolgus monkeys with a novel prototype selective androgen receptor modulator revealed trace amounts of an aniline fragment released through hydrolytic metabolism. This aniline fragment was determined to be mutagenic in an Ames assay. Subsequent concurrent optimization for target activity and avoidance of mutagenicity led to the identification of a pharmacologically superior clinical candidate without mutagenic potential.

Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals

There are provided novel anthranilonitrile derivatives and related compounds which are useful for promoting growth, improving feed efficiency and for increasing the lean meat to fat ratio of warm-blooded animals.