1123515-42-3

Basic information

• Product Name: N-(4-methyl-3-nitrophenyl)-5-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine
• Synonyms: N-(4-methyl-3-nitrophenyl)-5-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine
• CAS NO: 1123515-42-3
• Molecular Weight: 390.321
• Mol File: 1123515-42-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-methyl-3-nitrophenyl)-5-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methyl-3-nitrophenyl)-5-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine(1123515-42-3)
• EPA Substance Registry System: N-(4-methyl-3-nitrophenyl)-5-(4-(trifluoromethoxy)phenyl)pyrimidin-2-amine(1123515-42-3)

Safety Data

• Hazardous Substances Data: 1123515-42-3(Hazardous Substances Data)

Upstream product

• 1123515-36-5 5-bromo-N-(4-methyl-3-nitrophenyl)pyrimidin-2-amine 
• 139301-27-2 4-trifluoromethoxyphenylboronic acid 

Downstream Products

• 1123515-44-5 4-methyl-N₁-(5-(4-(trifluoromethoxy)phenyl)pyrimidin-2-yl)benzene-1,3-diamine 

Relevant articles and documents

5- (4- (HALOALKOXY) PHENYL) PYRIMIDINE-2-AMINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

The invention provides compounds of formula (1) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit, PDGFRα, PDGFRβ, CSF1R, AbI, BCR-AbI, CSK, JNK1, JNK2, p38, p70S6K, TGFβ, SRC, EGFR, trkB, FGFR3. Fes, Lck, Syk, RAF, MKK4, MKK6, SAPK2β, BRK, Fms, KDR, c-rapor b-raf kinases.