112446-85-2

Basic information

• Product Name: 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone
• Synonyms: 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone
• CAS NO: 112446-85-2
• Molecular Formula: C₂₅H₃₂N₂O
• Molecular Weight: 376.53438
• Mol File: 112446-85-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone(112446-85-2)
• EPA Substance Registry System: 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone(112446-85-2)

Safety Data

• Hazardous Substances Data: 112446-85-2(Hazardous Substances Data)

Usage

Description

1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone is a synthetic chemical compound with the molecular formula C26H32N2O. It is a potent μ-opioid receptor agonist, acting as a derivative of the opioid drug fentanyl. 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone features a cyclopentylphenyl group at the 1-position and a 4-phenylpiperazine group at the 4-position of the butanone chain, providing it with significant analgesic effects. However, it is also a potentially dangerous opioid with a high potency for abuse and addiction, leading to its classification as a controlled substance in many countries.

Uses

Used in Pharmaceutical Research:
1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone is used as a research compound for understanding the mechanisms of opioid receptors and their role in pain management. Its potent agonist activity makes it a valuable tool in studying the effects of opioids on the nervous system and developing new treatments for pain.
Used in Illicit Drug Market:
Unfortunately, due to its high potency and potential for abuse, 1-(4-cyclopentylphenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone is also used as an illicit substance in the drug market. Its presence in the illegal drug trade highlights the need for strict regulation and control measures to prevent abuse and addiction.

Upstream product

• 92-54-6 4-phenyl-1-piperazine 
• 57257-07-5 4-chloro-1-(4-cyclopentylphenyl)butan-1-one 
• 700-88-9 cyclopentylbenzene 

Relevant articles and documents

4-AMINO-1-(4-CYCLOPENTYLPHENYL)BUTAN-1-ONES; SYNTHESIS AND BIOLOGICAL SCREENING

4-Chloro-1-(4-cyclopentylphenyl)butan-1-one (IX), obtained by Friedel-Crafts reaction of cyclopentylbenzene with 4-chlorobutanoyl chloride, was subjected to substitution reactions with 4-phenylpiperidin-4-ol and a series of N-monosubstituted piperazines,