112497-43-5

Basic information

• Product Name: Benzenesulfonamide, N,4-dimethyl-N-2-propenyl-
• CAS NO: 112497-43-5
• Molecular Formula: C11H15NO2S
• Molecular Weight: 225.312
• Mol File: 112497-43-5.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N,4-dimethyl-N-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N,4-dimethyl-N-2-propenyl-(112497-43-5)
• EPA Substance Registry System: Benzenesulfonamide, N,4-dimethyl-N-2-propenyl-(112497-43-5)

Safety Data

• Hazardous Substances Data: 112497-43-5(Hazardous Substances Data)

Upstream product

• 107-05-1 3-chloroprop-1-ene 
• 640-61-9 N-methyl-p-toluenesulfonylamide 
• 591-87-7 Allyl acetate 
• 5183-78-8 methyl(phenylsulfonyl)amide 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 74-88-4 methyl iodide 
• 240132-49-4 N,4-dimethyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 1383926-73-5 N,4-dimethyl-N-(propa-1,2-dien-1-yl)benzenesulfonamide 
• 64-18-6 formic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 2520-97-0 N-allyl-N-α-methylbenzylamine 
• 627-37-2 N-methyl-N-allylamine 
• 373-68-2 tetramethylammonium fluoride 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 700336-75-0 N-methyl-N-(E)-prop-1-enyl 4-methylbenzenesulfonamide 
• 1082538-32-6 N,4-dimethyl-N-(2-oxoethyl)benzenesulfonamide 
• 501361-46-2 N-4-dimethyl-N-(3-phenylpropyl)benzenesulfonamide 
• 890662-14-3 N,4-dimethyl-N-(oxiran-2-ylmethyl)benzenesulfonamide 

Relevant articles and documents

Double C-N bond cleavages of: N-alkyl 4-oxopiperidinium salts: Access to unsymmetrical tertiary sulfonamides

In this paper, regiospecific, double intraannular C-N bond cleavages of N-alkyl 4-oxopiperidinium salts are presented. The reaction sequence involves a charge-transfer complex, in situ formed between sulfonyl chloride and N-methylmorpholine, which induces S-Cl bond homolysis of sulfonyl chloride, yielding a reactive sulfonyl radical that further induces the double C-N bond cleavages of N-alkyl 4-oxopiperidinium salt. The secondary amine thus produced was trapped by sulfonyl chloride to yield the desired sulfonamide product. The key feature of this protocol is that two intraannular C-N bonds of the 4-oxopiperidine ring are cleaved in one step under metal- A nd oxidant-free conditions.

Ligand-Controlled Regiodivergence for Catalytic Stereoselective Semireduction of Allenamides

Ligand-controlled regiodivergence has been developed for catalytic semireduction of allenamides with excellent chemo- and stereocontrol. This system also provides an example of catalytic regiodivergent semireduction of allenes for the first time. The divergence of the semireduction is enabled by ligand switch with the same palladium pre-catalyst under operationally simple and mild conditions. Monodentate ligand XPhos exclusively promotes selective 1,2-semireduction to afford allylic amides, while bidentate ligand BINAP completely switched the regioselectivity to 2,3-semireduction, producing (E)-enamide derivatives.

Selective Methylation of Amides, N-Heterocycles, Thiols, and Alcohols with Tetramethylammonium Fluoride

We herein disclose the use of tetramethylammonium fluoride (TMAF) as a direct and selective methylating agent of a variety of amides, indoles, pyrroles, imidazoles, alcohols, and thiols. The method is characterized by operational simplicity, wide scope, and ease of purification. Our computational studies suggest a concerted methylation-deprotonation as the preferred reaction pathway.