1126968-88-4

Basic information

• Product Name: 1-Benzyloxy-4-(pentafluorosulfanyl)benzene
• Synonyms: 1-Benzyloxy-4-(pentafluorosulfanyl)benzene;[4-(Phenylmethoxy)phenyl]sulfur pentafluoride
• CAS NO: 1126968-88-4
• Molecular Formula: C13H11F5OS
• Molecular Weight: 310.288
• Mol File: 1126968-88-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 87-93°C
• CAS DataBase Reference: 1-Benzyloxy-4-(pentafluorosulfanyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyloxy-4-(pentafluorosulfanyl)benzene(1126968-88-4)
• EPA Substance Registry System: 1-Benzyloxy-4-(pentafluorosulfanyl)benzene(1126968-88-4)

Safety Data

• Hazardous Substances Data: 1126968-88-4(Hazardous Substances Data)

Usage

Type of compound

Benzene derivative

Functional groups

a. Benzyloxy group
b. Pentafluorosulfanyl group

Usage

a. Building block in organic synthesis
b. Pharmaceutical and agrochemical industries

Pentafluorosulfanyl group

a. Valuable starting material for synthesis of novel fluorinated molecules
b. Unique and valuable properties of fluorinated molecules

Precursor

a. Synthesis of sulfonium salts
b. Important reagents in organic chemistry

Benzyloxy group

a. Easily modified to introduce different functional groups
b. Versatile and valuable intermediate in chemical synthesis

Upstream product

• 2613-27-6 1-nitro-4-(pentafluorosulfanyl)benzene 
• 100-51-6 benzyl alcohol 
• 774-93-6 1-bromo-4-pentafluorosulfanylbenzene 
• 286947-68-0 pentafluoro(4-iodophenyl)-λ⁶-sulfane 

Relevant articles and documents

DIARYLIODONIUM SALT

PROBLEM TO BE SOLVED: To provide a compound that allows easy introduction of a pentafluorosulfanylaryl group into a compound of interest. SOLUTION: A diaryliodonium salt is represented by the general formula (d) in the figure. (In the formula, k is 1 or 2, R1 is an alkyl group having 1 or 2 carbon atoms, m is an integer from 0 to 4, R2 is a straight or branched alkyl group having 1 to 4 carbon atoms, n is an integer from 0 to 5, and A- is a counter anion.) SELECTED DRAWING: None COPYRIGHT: (C)2016,JPO&INPIT

Synthesis of Diaryliodonium Salts Having Pentafluorosulfanylarenes and Their Application to Electrophilic Pentafluorosulfanylarylation of C-, O-, N-, and S-Nucleophiles

Novel reagents for the electrophilic introduction of pentafluorosulfanyl (SF5) arenes into target molecules are disclosed. Unsymmetrical diaryliodonium salts 1 having SF5-arenes were synthesized by a one-pot process from iodo-SF5-benzenes 2 in good yields. The SF5-aryliodonium salts 1 were found to be efficient for the electrophilic SF5-arylation of carbon and heterocentered nucleophiles to furnish the corresponding substituted SF5-arenes in good to high yields.

SNAr reactions of nitro-(pentafluorosulfanyl)benzenes to generate SF5 aryl ethers and sulfides

Nucleophilic aromatic substitution of the nitro group of para- and meta-nitro-(pentafluorosulfanyl)benzene with alkoxides and thiolates generates a range of substituted 4- and 3-(pentafluorosulfanyl)benzenes in a single-step reaction.