1127217-17-7Relevant articles and documents
Establishment of broadly applicable reaction conditions for the palladium-catalyzed direct arylation of heteroatom-containing aromatic compounds
Liegault, Benoit,Lapointe, David,Caron, Laurence,Vlassova, Anna,Fagnou, Keith
scheme or table, p. 1826 - 1834 (2009/07/01)
Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with aryl bromides are reported. Those conditions employ a stoichiometric ratio of both coupling partners, as well as a substoiehiometric quantity of pivalic acid, which results in significantly faster reactions. An evaluation of the influence of the nature of the aryl halide has also been carried out.