1128039-31-5Relevant articles and documents
2,2,3-Tribromopropanal as a versatile reagent in the skraup-type synthesis of 3-bromoquinolin-6-ols
Lamberth, Clemens,Kessabi, Fiona Murphy,Beaudegnies, Renaud,Quaranta, Laura,Trah, Stephan,Berthon, Guillaume,Cederbaum, Fredrik,Vettiger, Thomas,Prasanna
, p. 858 - 862 (2014/04/17)
2,2,3-Tribromopropanal, a reagent which almost became forgotten in the chemical literature after its first application in the 1950s, is used for the one-step transformation of diversely substituted 4-nitro- and 4-methoxyanilines into 3-bromo-6-nitroquinolines and 3-bromo-6-methoxyquinolines. These intermediates are then converted, in one further step, into 3-bromoquinolin-6- ols, which may carry additional substituents at positions 7 and 8. Georg Thieme Verlag Stuttgart New York.
