112883-39-3 Usage
Description
Fmoc-D-Aspartic acid beta-tert-butyl ester, also known as Fmoc-d-asp(otbu)-OH, is a white to light yellow crystalline powder with specific chemical properties. It is a derivative of aspartic acid, an amino acid commonly found in proteins, and is modified with a fluorenylmethoxycarbonyl (Fmoc) group and a beta-tert-butyl ester group. Fmoc-D-Aspartic acid beta-tert-butyl ester is widely utilized in the field of organic chemistry and pharmaceuticals due to its unique structure and reactivity.
Uses
Used in Pharmaceutical Industry:
Fmoc-D-Aspartic acid beta-tert-butyl ester is used as a building block for the solid-phase synthesis of peptides and proteins. Its application is crucial in the development of novel therapeutic agents, including those with potential anticancer, antiviral, and antibacterial properties. The compound's unique structure allows for the efficient and selective incorporation of D-aspartic acid into peptide sequences, which can be essential for the biological activity of the final product.
Used in Organic Chemistry:
Fmoc-D-Aspartic acid beta-tert-butyl ester is used as a reactant for the solid-phase preparation of tripeptides. This application is particularly important in asymmetric synthesis, where the compound serves as a key intermediate in the preparation of various chiral molecules, such as nitroalkanals. The use of this compound in asymmetric synthesis can lead to the development of enantiomerically pure compounds, which are highly valuable in the pharmaceutical industry due to their potential for improved efficacy and reduced side effects.
Used in Research and Development:
Fmoc-D-Aspartic acid beta-tert-butyl ester is also used as a research tool in the study of peptide synthesis, protein structure, and function. Its unique properties make it an attractive candidate for investigating the role of D-amino acids in biological systems and for developing new methods for the synthesis of complex peptide structures. Additionally, the compound can be used to explore the potential applications of D-amino acid-containing peptides in various fields, such as drug discovery, diagnostics, and biomaterials.
Check Digit Verification of cas no
The CAS Registry Mumber 112883-39-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,8,8 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 112883-39:
(8*1)+(7*1)+(6*2)+(5*8)+(4*8)+(3*3)+(2*3)+(1*9)=123
123 % 10 = 3
So 112883-39-3 is a valid CAS Registry Number.
InChI:InChI=1/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m1/s1
112883-39-3Relevant articles and documents
GLP-2 compounds, formulations, and uses thereof
-
, (2008/06/13)
The present invention relates to novel human glucagon-like peptide-2 (GLP-2) peptides and human glucagon-like peptide-2 derivatives which have a protracted profile of action as well as polynucleotide constructs encoding such peptides, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.
