113201-95-9 Usage
General Description
10H-Phenoxazine, 4-(methylthio)-10-(1-phenylethyl)-, also known as methylene blue, is a synthetic organic compound with a deep blue color. It is commonly used as a redox indicator, a dye, and a medication for various medical conditions. Methylene blue has been found to have antimicrobial, antimalarial, and antiprotozoal properties, making it useful in the treatment of methemoglobinemia, malaria, and urinary tract infections. Additionally, its potential neuroprotective and neurorestorative effects have garnered attention for its potential use in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. However,
Check Digit Verification of cas no
The CAS Registry Mumber 113201-95-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,2,0 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 113201-95:
(8*1)+(7*1)+(6*3)+(5*2)+(4*0)+(3*1)+(2*9)+(1*5)=69
69 % 10 = 9
So 113201-95-9 is a valid CAS Registry Number.
113201-95-9Relevant articles and documents
Regiospecific Lithiation of Phenoxazine Ortho to the Oxygen Atom. Synthesis of 4-Mono- and 4,6-Disubstituted Phenoxazine Derivatives
Antonio, Yulia,Barrera, Patricia,Contreras, Olga,Franco, Fidencio,Galeazzi, Edvige,et al.
, p. 2159 - 2165 (2007/10/02)
Under appropriate conditions, phenoxazine bearing a sterically demanding, bulky N-substituent (e.g., α-methylbenzyl or tert-butyldimethylsilyl) undergoes lithiation at C-4 or at C-4 and C-6 with n-butyllithium in THF solution.The lithiated species react with a variety of electrophilic reagents and upon subsequent N-deprotection provide access to 4-mono- or 4,6-disubstituted phenoxazines.This process is of particular synthetic utility (36-54percent yields) when the N-substituent is tert-butyldimethylsilyl.