113246-37-0Relevant articles and documents
Novel β-amino acid derivatives as inhibitors of cathepsin A
Ruf, Sven,Buning, Christian,Schreuder, Herman,Horstick, Georg,Linz, Wolfgang,Olpp, Thomas,Pernerstorfer, Josef,Hiss, Katrin,Kroll, Katja,Kannt, Aimo,Kohlmann, Markus,Linz, Dominik,Hübschle, Thomas,Rütten, Hartmut,Wirth, Klaus,Schmidt, Thorsten,Sadowski, Thorsten
, p. 7636 - 7649 (2012/11/07)
Cathepsin A (CatA) is a serine carboxypeptidase distributed between lysosomes, cell membrane, and extracellular space. Several peptide hormones including bradykinin and angiotensin I have been described as substrates. Therefore, the inhibition of CatA has
Reaction of Hydrazonyl Chlorides and Carboalkoxymethylene Triphenylphosphoranes to Give 5-Alkoxy Substituted Pyrazoles
Padwa, Albert,MacDonald, J. Gavin
, p. 1225 - 1227 (2007/10/02)
The reaction of ethyl chloroglyoxylate phenyl hydrazone and diphenyl hydrazonyl chloride with several carboalkoxymethylene triphenylphosphoranes has been examined.The products isolated correspond to N-phenyl-3-carboalkoxy-5-alkoxy substituted pyrazoles.Th