113296-74-5Relevant articles and documents
Improvements in aldol reactions with diketopiperazines
Gonzalez, Juan Francisco,De La Cuesta, Elena,Avendano, Carmen
, p. 1589 - 1597 (2007/10/03)
Precipitation of products by using dichloromethane as solvent permits an efficient aidol-type reaction between 1,4-diacetyl-2,5-piperazinedione and aromatic aldehydes catalyzed by KtBuO/tBuOH independently of the electrophilic character of the aryl ring. A simple method to obtain 3-methyl-2,4,5-trimethoxybenzaldehyde is also reported.