113307-19-0

Basic information

• Product Name: 2,4-Pentadienoic acid, 2-fluoro-5-phenyl-, ethyl ester, (Z,E)-
• CAS NO: 113307-19-0
• Molecular Formula: C13H13FO2
• Molecular Weight: 220.243
• Mol File: 113307-19-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,4-Pentadienoic acid, 2-fluoro-5-phenyl-, ethyl ester, (Z,E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Pentadienoic acid, 2-fluoro-5-phenyl-, ethyl ester, (Z,E)-(113307-19-0)
• EPA Substance Registry System: 2,4-Pentadienoic acid, 2-fluoro-5-phenyl-, ethyl ester, (Z,E)-(113307-19-0)

Safety Data

• Hazardous Substances Data: 113307-19-0(Hazardous Substances Data)

Upstream product

• 910803-66-6 ethyl α-(1,3-benzothiazol-2-ylsulfonyl)-α-fluoroacetate 
• 14371-10-9 (E)-3-phenylpropenal 
• 401-55-8 ethyl bromofluoroacetate 
• 28620-50-0 α-(trans-2-phenyl-ethenyl)-N-phenylnitrone 
• 459-72-3 ethyl 2-fluoroacetate 
• 4392-24-9 Cinnamyl bromide 
• 864363-35-9 (E)-2-Fluoro-3-hydroxy-5-phenyl-2-phenylselanyl-pent-4-enoic acid ethyl ester 
• 7582-61-8 diethyl 2-oxo-3-fluorobutan-1,4-dioate sodium salt 
• 401-58-1 ethyl 2-fluoro-2-iodoacetate 

Relevant articles and documents

An Expedient Stereoselective Access to (Z)-2-Fluoroalkenoates

The reaction between an aldehyde R-CHO and diethyl 2-oxo-3-fluorobutan-1,4-dioate as its sodium salt EtO2C-CO-CF-CO2Et-,Na+ mainly leads in THF to (Z)-2-fluoroalkenoates R-CH=CF-CO2Et (Z/E>/=80/20), the Z-stereoselectivity depending on the bulk of the R group.Key words: 2-Fluoroalkenoates; (Z)-stereoselective synthesis.

A convenient method for the synthesis of (Z)-α-fluoroacrylates: Lewis base-catalyzed carbonyl fluoroolefination using fluoro(trimethylsilyl)ketene ethyl trimethylsilyl acetal

A highly useful method is established for the stereoselective synthesis of (Z)-α-fluoroacrylates from various aldehydes and fluoro(trimethylsilyl) ketene ethyl trimethylsilyl acetal in the presence of a Lewis base catalyst. The ketene acetal, easily prepared from ethyl fluoroacetate, affords α-fluoroacrylates in high yields with excellent Z stereoselectivities under mild conditions. Copyright

Z-selective or stereospecific alkenylation reaction: A novel synthetic method for α-fluoro-α,β-unsaturated esters

The Z-selective formation of α-fluoro-α,β-unsaturated esters was achieved using the deselenenic acid of the syn-and/or anti-3-aryl-2-fluoro-3-hydroxy-2-organoselanylacetates 3 and 4 with trifluoromethanesulfonic acid. In contrast, the 3-alkyl-substituted propanoates 3f and 4b stereospecifically underwent alkenylation to give the (E)- or (Z)-α-fluoro-α,β-unstaurated esters 5f. We were also successful in the one-pot alkenylation reactions. Copyright