113368-98-2

Basic information

• Product Name: Phosphonic acid, [2-oxo-2-[(phenylmethyl)amino]ethyl]-, bis(1-methylethyl) ester
• CAS NO: 113368-98-2
• Molecular Formula: C15H24NO4P
• Molecular Weight: 313.334
• Mol File: 113368-98-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-oxo-2-[(phenylmethyl)amino]ethyl]-, bis(1-methylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-oxo-2-[(phenylmethyl)amino]ethyl]-, bis(1-methylethyl) ester(113368-98-2)
• EPA Substance Registry System: Phosphonic acid, [2-oxo-2-[(phenylmethyl)amino]ethyl]-, bis(1-methylethyl) ester(113368-98-2)

Safety Data

• Hazardous Substances Data: 113368-98-2(Hazardous Substances Data)

Upstream product

• 123-46-6 girard's reagent T 
• 100-46-9 benzylamine 
• 72946-10-2 diisopropyl (methoxycarbonylmethyl)phosphonate 

Relevant articles and documents

Column chromatography-free solution-phase synthesis of a natural piper-amide-like compound library

We have achieved an efficient solution-phase parallel synthesis of a library of natural piper-amide-like compounds from the bifunctional β-phosphono-N-hydroxy-succinimidyl ester intermediate. The primary important feature in our study is the construction of natural-product-like molecules through the adaptation of sophisticated organic reactions that create water-soluble byproducts for a chromatography-free purification. This simple and efficient method rapidly provides a combinatorial library of high yield and purity. The library was evaluated against GPCR targets to demonstrate its potential use as a tool for drug discovery and in chemical biology.