1134-36-7

Basic information

• Product Name: 2-AMINO-4-PHENYLPHENOL
• Synonyms: 1’-biphenyl]-4-ol,3-amino-[;2-hydroxy-5-phenylaniline;3-amino-(1,1’-biphenyl)-4-ol;3-amino-4-biphenylo;4-phenyl-2-aminophenol;nsc7950;2-AMINO-4-PHENYLPHENOL, TECH., 90%;2-AMINO-4-PHENYLPHENOL 98+%
• CAS NO: 1134-36-7
• Molecular Formula: C₁₂H₁₁NO
• Molecular Weight: 185.22
• EINECS: 214-484-8
• Product Categories: Organic Building Blocks;Oxygen Compounds;Phenols
• Mol File: 1134-36-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 198-202 °C(lit.)
• Boiling Point: 356 °C at 760 mmHg
• Flash Point: 169.1 °C
• Appearance: White to light brown/Powder
• Density: 1.191 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 9.66±0.18(Predicted)
• CAS DataBase Reference: 2-AMINO-4-PHENYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-PHENYLPHENOL(1134-36-7)
• EPA Substance Registry System: 2-AMINO-4-PHENYLPHENOL(1134-36-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 2
• RTECS: DV6037500
• Hazardous Substances Data: 1134-36-7(Hazardous Substances Data)

Usage

Description

2-Amino-4-phenylphenol is an aminoalcohol derivative that plays a significant role in the synthesis of bisbenzoxazoles. It is a versatile compound with various applications across different industries.

Uses

Used in Pharmaceutical Research:
2-Amino-4-phenylphenol is used as an internal standard to investigate the enzymatic activity of N-hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA), a mammary gland carcinogen in the female Sprague-Dawley rat, by High-Performance Liquid Chromatography (HPLC). This application aids in understanding the metabolic pathways and detoxification processes of carcinogenic compounds.
Used in Chemical Synthesis:
2-Amino-4-phenylphenol is used as a chelating agent for metal ions, which is crucial in various chemical reactions and processes. Its ability to form stable complexes with metal ions helps in controlling reaction rates, enhancing product yields, and improving the overall efficiency of chemical synthesis.
Used in Synthesis of Bisbenzoxazoles:
2-Amino-4-phenylphenol is a key component in the synthesis of bisbenzoxazoles, which are important compounds with potential applications in pharmaceuticals, materials science, and other fields. Its involvement in the synthesis process contributes to the development of novel and innovative bisbenzoxazole-based compounds with diverse properties and functions.

Upstream product

• 21524-23-2 3-Phenylazo-biphenyl-4-ol 
• 885-82-5 4-phenyl-2-nitrophenol 
• 40925-68-6 2-amino-4-bromo-phenol 
• 98-80-6 phenylboronic acid 
• 39811-17-1 5-phenyl-O-anisidine 

Downstream Products

• 61931-68-8 2-methyl-5-phenylbenzo[d]oxazole 
• 65407-95-6 2,5-diphenylbenzo[d]oxazole 
• 71860-26-9 3-(5-phenylbenzo[d]oxazol-2-yl)-2H-chromen-2-one 
• 16156-01-7 2-(4-methylphenyl)-5-phenylbenzoxazole 
• 25847-90-9 1-(3,5-Bis-trifluoromethyl-phenyl)-3-(4-hydroxy-biphenyl-3-yl)-urea 
• 109648-57-9 3-Phenyl-6-hydroxy-thiocarbanilsaeure-(4-methoxy-phenyl-ester) 
• 27393-24-4 6-phenyl-4H-benzo[1,4]oxazine-2,3-dione 
• 17371-99-2 5-phenylbenzo[d]oxazole-2-thiol 
• 76826-00-1 (2-Hydroxy-5-phenyl-phenylimino)triphenylphosphoran 
• 173312-46-4 N-(4-hydroxy-3-biphenyl)-2-methoxydibenzofuran-3-carboxamide 
• 25108-26-3 2-phenyl-benzo[4,5]oxazolo[3,2-b]isoquinolin-11-one 
• 15657-87-1 8-hydroxy-5-(phenyl)quinoline 
• 17371-99-2 5-phenyl-3H-benzooxazole-2-thione 

Relevant articles and documents

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY

The present invention generally concerns particular methods and compositions for antimicrobial therapy. In particuarl embodiments, the compositions target DXR. In specific embodiments, the compositions are electron-deficient heterocyclic rings.

4-Hydroxyquinolone-(2)-azomethine copper complex pigments

A compound having the formula STR1 wherein A denotes an optionally substituted aromatic, isocyclic or heterocyclic residue; R is H, an alkyl residue having from 1 to 6 carbon atoms, an aryl residue having from 6 to 10 carbon atoms or an aralkyl residue having from 7 to 10 carbon atoms; Q is H or a methyl group; X and Y are the same or different and each is a non-water solubilizing group, or X and Y together form a fused aromatic ring system; and R1 and R2 are the same or different and each is H or an alkyl radical having from 1 to 22 carbon atoms, and R3 is hydrogen, an alkyl radical having from 1 to 22 carbon atoms or an aryl radical having from 6 to 10 carbon atoms, the alkyl radicals in R1, R2 and R3 being unsubstituted and uninterrupted or being substituted by an OH, NH2 or CN group and/or being interrupted by an ethylenic group or an oxygen, sulphur or nitrogen bridge, or two or all three of R1, R2 and R3 may form, together with the nitrogen atom to which they are attached, a heterocyclic residue, is useful for pigmenting high molecular weight organic material such as a natural or synthetic polymer or copolymer, or a coating composition for application to the surface of an article, or a printing liquid medium to yield shades from greenish yellow to red brown, exhibiting good fastness properties.