113544-32-4Relevant articles and documents
ESTERS OF ARYLPROPIONIC ACIDS WITH 1,2:5,6-DI-O-ISOPROPYLIDENE- AND 1,2-O-ISOPROLYLIDENE-α-D-GLUCOFURANOSE
Svoboda, Jiri,Capek, Karel,Palecek, Jaroslav
, p. 766 - 774 (2007/10/02)
On fractional crystallization of 3-O-(2-(2-fluoro-4-biphenylyl)propionyl-, 3-O-(2-(4-isobutylphenyl)propionyl)- and 3-O-(2-(6-methoxy-2-naphthyl)propionyl)-1,2:5,6-di-O-isopropylidene-α-D-glucofuranoses V - VII optically pure R-diastereoisomers were isolated.The derivatives of 1,2-O-isopropylidene-α-D-glucofuranose obtained on partial deacetylation of esters V - VII were separated chromatographically to R and S-diastereoisomers.Their hydrolysis or transesterification afforded optically pure arylpropionic acids or their methyl esters, respectively.Kinetic resolutionof the acids gives rise to esters V - VII enriched in R-diastereoisomer.