113964-33-3

Basic information

• Product Name: Silane, (6-chloro-1-hexynyl)trimethyl-
• CAS NO: 113964-33-3
• Molecular Formula: C9H17ClSi
• Molecular Weight: 188.772
• Mol File: 113964-33-3.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Silane, (6-chloro-1-hexynyl)trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (6-chloro-1-hexynyl)trimethyl-(113964-33-3)
• EPA Substance Registry System: Silane, (6-chloro-1-hexynyl)trimethyl-(113964-33-3)

Safety Data

• Hazardous Substances Data: 113964-33-3(Hazardous Substances Data)

Upstream product

• 10297-06-0 1-chloro-5-hexyne 
• 75-77-4 chloro-trimethyl-silane 
• 10297-05-9 1-chloro 4-iodobutane 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 127016-37-9 triphenyl(6-(trimethylsilyl)-5-hexynyl)phosphonium iodide 
• 1092444-48-8 tert-butyl (R)-benzyl-{5-[1-(tert-butyl-dimethylsilyloxy)-9-(6-fluoropyridin-3-yl)-non-2-ylamino]-3-isopropyl-pyrazolo[1,5-a]pyrimidin-7-yl}carbamate 
• 1092444-49-9 tert-butyl benzyl-((R)-5-(9-(6-fluoropyridin-3-yl)-1-hydroxynonan-2-ylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-yl)carbamate 
• 91656-99-4 (5-bromo-pent-1-ynyl)-trimehyl-silane 
• 144136-74-3 2-(4-chlorobutyl)-3-ethyl-4-(benzyloxymethyl)-1-(trimethylsilyl)-1,4-pentadiene 
• 144136-75-4 4-(benzyloxymethyl)-2-(4-chlorobutyl)-1-(trimethylsilyl)-1,4-heptadiene 
• 144115-81-1 <1-(2)H1>-4-(benzyloxymethyl)-2-(4-chlorobutyl)-1-(trimethylsilyl)-1,4-pentadiene 
• 113964-39-9 1-(4-chlorobutyl)-4-methylene-2-(trimethylsilyl)-1-cyclopentene 
• 1268810-13-4 2-cyclobutylethynyl(trimethyl)silane 

Relevant articles and documents

Intramolecular Metallo-Ene-Allene Reactions. A New Carbocycles Synthesis

Polysubstituted enynes have been lithiated on the propargylic position, and transmetalation to the corresponding zinc reagents promotes an easy cyclization reaction leading to polysubstituted cyclopentylmethylzinc derivatives.This cyclization is stereospecific, and a single diastereoisomer is formed, even when a tertiary and a quaternary center are linked in the process.The reaction is considered to take place via a metallo-ene-allene process.

A Commercially Available and User-Friendly Catalyst for Hydroamination Reactions under Technical Conditions

The activity of a simple, commercially available copper salt, [Cu(NCMe)4](BF4) in intramolecular hydroamination reactions of alkynes and allenes is presented. Reactions were successfully carried out in technical acetonitrile in the presence of air. While attempts of alkene hydroamination failed, this catalyst was also found active in intermolecular aza-Michael reactions.

Regioselective Allylation of Carbon Electrophiles with Alkenyl-silanes under Dual Catalysis by Cationic Platinum(II) Species

In the presence of catalytic amounts of platinum(II) chloride and silver(I) hexafluoroantimonate, (Z)-alkenylsilanes reacted with various carbon electrophiles (acetals, aminals, carboxylic anhydrides, alkyl chlorides, etc.) at the γ-position to give allylation products. A plausible mechanism for the platinum-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles, both of which are catalyzed by a cationic platinum(II) species.

ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.