114300-89-9Relevant articles and documents
Asymmetric [3 + 2] cycloaddition of 2,3-butadienoates with electron-deficient olefins catalyzed by novel chiral 2,5-dialkyl-7-phenyl-7-phosphabicyclo[2.2.1]heptanes
Zhu,Chen,Jiang,Xiao,Cao,Zhang
, p. 3836 - 3837 (1997)
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Synthesis of optically active 2,5-dialkylcyclohexane-1,4-diols and their application in the asymmetric oxidation of sulfides
Sun, Jiangtao,Yang, Minghua,Dai, Zhenya,Zhu, Chengjian,Hu, Hongwen
scheme or table, p. 2513 - 2518 (2009/04/11)
A simple and efficient approach to obtain optically pure 1,4-diols was established. The asymmetric oxidation of sulfides to sulfoxides with cumyl hydroperoxide in moderate yields and moderate to high enantioselectivities (up to 84%) catalyzed by chiral Ti/ 1,4-diols complexes has been achieved. A 76% ee value was obtained in the asymmetric synthesis of esomeprazole. Georg Thieme Verlag Stuttgart.