1144516-95-9

Basic information

• Product Name: TF3BOK
• Synonyms: 2,6-Bis(trifluoroMethyl)benzoic Acid 3-AMino-2-oxopropyl Ester 4-Methylbenzenesulfonate;2,6-TrifluoroMethylbenzyloxy Glycine Methyl Ketone Tosylate;TF3BOK
• CAS NO: 1144516-95-9
• Molecular Formula: C19H17F6NO6S
• Molecular Weight: 501.3967992
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 1144516-95-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TF3BOK(CAS DataBase Reference)
• NIST Chemistry Reference: TF3BOK(1144516-95-9)
• EPA Substance Registry System: TF3BOK(1144516-95-9)

Safety Data

• Hazardous Substances Data: 1144516-95-9(Hazardous Substances Data)

Usage

Description

TF3BOK, also known as 2,6-Trifluoromethylbenzyloxy Glycine Methyl Ketone, is a chemical compound used in the synthesis of electrophilic glycine analogs. It plays a crucial role in the identification and mechanistic study of the ubiquitin conjugating machinery, which is essential for various cellular processes.

Uses

Used in Chemical Synthesis:
TF3BOK is used as a key intermediate in the synthesis of electrophilic glycine analogs, which are important for the development of new chemical compounds and materials.
Used in Biological Research:
In the field of biological research, TF3BOK is used as an activity-based probe for the identification and mechanistic study of the ubiquitin conjugating machinery. This machinery is involved in various cellular processes, including protein degradation, signal transduction, and DNA repair. Understanding the function and regulation of this machinery can provide valuable insights into the underlying mechanisms of various diseases and potential therapeutic targets.
Used in Drug Development:
TF3BOK's role in the synthesis of electrophilic glycine analogs makes it a valuable tool in the development of new drugs targeting the ubiquitin conjugating machinery. These drugs could potentially be used to treat a wide range of diseases, including cancer, neurodegenerative disorders, and inflammatory conditions, by modulating the activity of specific proteins involved in these processes.
Used in Diagnostics:
The ability of TF3BOK to act as an activity-based probe for the ubiquitin conjugating machinery also makes it a useful tool in the development of diagnostic tests. These tests could help identify individuals with specific genetic mutations or alterations in the ubiquitin system, allowing for more personalized and targeted treatment approaches.