1145785-99-4

Basic information

• Product Name: N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine
• Synonyms: N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine
• CAS NO: 1145785-99-4
• Molecular Weight: 417.486
• Mol File: 1145785-99-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine(1145785-99-4)
• EPA Substance Registry System: N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine(1145785-99-4)

Safety Data

• Hazardous Substances Data: 1145785-99-4(Hazardous Substances Data)

Upstream product

• 66399-30-2 (S)-1-(4-Fluoro-phenyl)-ethylamine 
• 1145786-45-3 [4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]boronic acid 
• 1145786-64-6 6-chloro-N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-3-pyridazinamine 
• 1145786-44-2 4-methyl-1-[2-(methyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazole 

Downstream Products

• 1145785-98-3 N-[(1S)-1-(4-fluorophenyl)ethyl]-5-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine hydrochloride 

Relevant articles and documents

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SAR of a novel series of pyridazine-derived γ-secretase modulators is described. Compound 25 was found to be a potent modulator in vitro, which on further profiling, was found to decrease Aβ42 and Aβ40, and maintain the levels of total Aβ. Furthermore, 25