1146214-77-8 Usage
Description
Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a benzoic acid ester that is derived from benzoic acid and methanol, featuring a boron atom within its structure. This organic compound is widely recognized for its utility as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its boron group endows it with unique reactivity, making it a valuable component in organic synthesis, particularly for carbon-carbon bond formation through the Suzuki-Miyaura coupling method.
Uses
Used in Pharmaceutical Industry:
Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence in the structure allows for the creation of new molecules with potential therapeutic properties, contributing to the development of novel drugs.
Used in Agrochemical Industry:
In the agrochemical sector, this compound serves as an intermediate for the production of various agrochemicals. Its role in the synthesis process is crucial for developing new compounds that can be used in agriculture to protect crops and enhance yields.
Used in Organic Synthesis:
Methyl 2-methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a reagent in organic synthesis, particularly for the formation of carbon-carbon bonds through the Suzuki-Miyaura coupling reaction. This method is highly valued for its ability to join aryl and vinyl halides to arylboronic acids or esters, facilitating the creation of complex organic molecules with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1146214-77-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,2,1 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1146214-77:
(9*1)+(8*1)+(7*4)+(6*6)+(5*2)+(4*1)+(3*4)+(2*7)+(1*7)=128
128 % 10 = 8
So 1146214-77-8 is a valid CAS Registry Number.
1146214-77-8Relevant articles and documents
Synthesis of thioxanthones through formal C-H thiolation of benzoic acid esters and Acid-mediated Direct Cyclization
Hosoya, Takamitsu,Mutsuura, Kotaro,Sakata, Yuki,Uchida, Keisuke,Yoshida, Suguru
, p. 753 - 756 (2020)
An efficient thioxanthone synthesis from benzoic acid esters is disclosed. Various thioxanthones were prepared by iridiumcatalyzed C-H borylation of benzoic acid esters followed by copper-catalyzed deborylthiolation and direct acid-mediated cyclization. We also achieved a synthesis of benzo-fused thioxanthones through a transformation of an aryne intermediate having an ester moiety.
Selenium-catalyzed C(sp3)-H acyloxylation: Application in the expedient synthesis of isobenzofuranones
Kr?tzschmar, Felix,Kassel, Martin,Delony, Daniel,Breder, Alexander
, p. 7030 - 7034 (2015/05/05)
Oxidative Se-catalyzed C(sp3)-H bond acyloxylation has been used to construct a diverse array of isobenzofuranones from simple ortho-allyl benzoic acid derivatives. The synthetic procedure employs mild reaction conditions and gives high chemoselectivity enabled by an inexpensive organodiselane catalyst. The presented approach offers a new synthetic pathway toward the core structures of phthalide natural products.
Directed ortho borylation of functionalized Arenes catalyzed by a silica-supported compact phosphine-iridium system
Kawamorita, Soichiro,Ohmiya, Hirohisa,Hara, Kenji,Fukuoka, Atsushi,Sawamura, Masaya
, p. 5058 - 5059 (2009/09/30)
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