114672-01-4

Basic information

• Product Name: ethyl 1-benzylcyclobutanecarboxylate
• Synonyms: ethyl 1-benzylcyclobutanecarboxylate
• CAS NO: 114672-01-4
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.29152
• Mol File: 114672-01-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ethyl 1-benzylcyclobutanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-benzylcyclobutanecarboxylate(114672-01-4)
• EPA Substance Registry System: ethyl 1-benzylcyclobutanecarboxylate(114672-01-4)

Safety Data

• Hazardous Substances Data: 114672-01-4(Hazardous Substances Data)

Usage

General Description

Ethyl 1-benzylcyclobutanecarboxylate, also known as ethyl benzylcyclobutanecarboxylate, is a chemical compound with the molecular formula C15H18O2. It is a colorless liquid with a pleasant floral odor, commonly used in the fragrance and flavor industry for its sweet, floral aroma. ethyl 1-benzylcyclobutanecarboxylate is often used as a fragrance ingredient in cosmetic and personal care products, as well as in the production of perfumes, soaps, and detergents. Ethyl 1-benzylcyclobutanecarboxylate is also used in the synthesis of pharmaceuticals and can act as a precursor in organic chemistry reactions. However, it is important to handle this compound with care, as it can be irritating to the skin, eyes, and respiratory system and should be used in a well-ventilated environment.

Upstream product

• 14924-53-9 ethyl cyclobutylcarboxylate 
• 100-39-0 benzyl bromide 
• 97-62-1 Ethyl isobutyrate 
• 35120-18-4 ethyl 1-bromocyclobutane-1-carboxylate 
• 62673-31-8 benzyl(bromo)zinc 

Downstream Products

• 433219-87-5 (1-benzyl-cyclobutyl)-methanol 
• 568591-06-0 {(S)-1-[Hydroxy-((R)-1-phenyl-ethylcarbamoyl)-methyl]-pentyl}-carbamic acid 1-benzyl-cyclobutylmethyl ester 
• 114672-02-5 1-benzylcyclobutane-1-carboxylic acid 
• 1255306-38-7 1-benzylcyclobutanecarbonyl azide 

Relevant articles and documents

Formation of quaternary carbons through cobalt-catalyzed C(sp3)-C(sp3) Negishi cross-coupling

Formation of all-carbon-substituted quaternary carbons is a key challenge in organic and medicinal chemistry. We report a cobalt-catalyzed C(sp3)-C(sp3) cross-coupling that allows for the introduction of benzyl, heteroarylmethylzinc and allyl groups to halo-carbonyl substrates. The cross-coupling reaction is selective for C(sp3)-over C(sp2)-halides, in contrast to most used catalytic metals, and allows access to novel scaffolds of pharmaceutical interest. NMR mechanistic studies suggest the presence of Co(0) complexes as catalytic species. This journal is

CYCLOBUTENEDIONE DERIVATIVES

The present invention relates to compounds of the formula (I): to pharmaceutically acceptable salts therefore and to pharmaceutically acceptable solvates of said compounds and salts, wherein the substituents are defined herein; to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly inflammatory conditions.